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Table 4 Hierarchical bivariate and multivariable determinants of NCD DALYs among adolescents in 194 countries, 2015

From: Non-communicable diseases among adolescents: current status, determinants, interventions and policies

Domain/Indicator

Outcome: DALYs attributed to NCDs among adolescents (rate, 2015)

 

Bivariate

Multivariable

 

R-Square

Î’ estimate (Standard error)

P-value

StB

Î’ estimate (Standard error)

P-value

Level 3 Model- Distal: Macro Structural Factors a

Conflict

Source & Year

    

Battle related deaths (total; log)

World Bank, 2013

1%

−23.5 (16.92)

0.1673

− 0.10

–

Internally displaced persons (total; log)

World Bank, 2013

1%

−21.8 (24.92)

0.3838

− 0.07

–

Refugee populations by country of asylum (total; log)

World Bank, 2014

16%

−58.3 (10.31)

<.0001

− 0.39

−19.8 (8.13)

0.0156

Governance

Political stability/absence of terrorism

World Bank, 2013

0%

−11.3 (60.98)

0.8534

−0.01

–

Government effectiveness 1

World Bank, 2013

11%

−264.4 (56.03)

<.0001

−0.33

− 442.4 (44.27)

<.0001

Corruption 1

World Bank, 2013

10%

−245.9 (56.74)

<.0001

−0.31

–

Environment

 Frequency of natural disasters (total; log)

 

0%

−72.2 (84.02)

0.3914

−0.07

–

 Cost damage of natural disasters (USD; log)

 

2%

−11.7 (6.91)

0.0924

−0.13

–

 

Distal Model R2:

38%

Level 2 Model- Intermediate I: National Structural Factors b

 Infrastructure and Urbanization

  Urbanization (% of population; log)

UNICEF, 2016

14%

− 597.0 (111.74)

<.0001

−0.37

− 261.0 (120.39)

0.0316

  Access to electricity (% population; cubed)

World Bank

9%

−0.00057 (0.00014)

<.0001

−0.30

− 0.0005 (0.00016)

0.0014

 Population Density

  Population density (people per m2 land; log)

World Bank

2%

−91.2 (43.15)

0.036

−0.16

−52.8 (33.41)

0.1162

 Telecommunications Access

  Mobile cellular subscriptions (per 100 people; log)

World Bank, 2014

3%

− 266.1 (114.17)

0.0209

−0.17

–

  Internet users (per 100 people; log)

World Bank, 2014

6%

−147.7 (43.14)

0.0008

−0.25

–

 National Wealth

  GDP per capita, 5 year lag (USD; log) 3

World Bank, 2014

11%

−172.9 (37.70)

<.0001

−0.33

–

 Health Spending

  Government expenditure on health, 2 year lag (% of total health expenditure; log)

WHO, 2013

1%

−165.0 (151.16)

0.2766

−0.08

–

  Total health expenditure per capita, 2 year lag (PPP, NCU per USD; log) 3

WHO, 2013

12%

− 169.7 (34.83)

<.0001

−0.34

−111.3 (62.56)

0.0771

 

Intermediate I Model R2:

47%

Level 3- Intermediate II: Community, Household & Individual Factors c

 Socioeconomic Status (Education and Employment)

  Adult literacy rate (% of adults ages 15+ years; cubed)

World Bank

1%

−0.00024 (0.00022)

0.2767

−0.10

 

  Primary school enrolment ratio (gross %; log)

World Bank, 2003–2014

1%

719.0 (499.43)

0.1519

0.11

 

  Secondary school enrolment ratio (gross %; log)

World Bank, 2013

7%

− 496.9 (144.18)

0.0007

−0.27

 

  Employment to population ratio (% of adults 15+ years; log)

World Bank

4%

724.5 (282.59)

0.0112

0.19

 

 Youth Empowerment

  Youth literacy rate (% total 15–24 year olds; squared)

World Bank, 2014

3%

−0.1 (0.03)

0.0718

−0.16

–

  Female youth literacy rate (% 15–24 year olds; squared)

World Bank, 2014

2%

−0.04 (0.03)

0.1169

− 0.14

–

  Youth unemployment rate (% total 15–24 year olds; log)

World Bank, 2013

1%

−95.3 (76.09)

0.212

− 0.10

–

  Adolescent fertility rate (births per 1000 females aged 15–19 years; log)

World Bank, 2009–2014

12%

256.0 (52.22)

<.0001

0.34

224.4 (66.17)

0.0009

 Women Empowerment and Gender Equity

  Total fertility rate (births per woman; log)

World Bank, 2013

7%

454.5 (122.04)

0.0003

0.27

–

  Adult female literacy rate (% females 15+ years who can read and write; cubed)

World Bank

0.5%

−0.016 (0.021)

0.4481

−0.07

–

  Women in parliament (% of parliamentary seats held by women; log)

World Bank, 2014

4%

−92.3 (35.97)

0.0111

−0.19

–

  Secondary school gender parity index (ratio of girls to boys in secondary education; log)

World Bank, 2013

3%

− 877.5 (416.20)

0.0366

−0.17

− 700.4 (341.58)

0.0422

  Tertiary school gender parity index (ratio of girls to boys in tertiary education; log)

World Bank, 2013

6%

− 206.4 (66.82)

0.0024

− 0.25

–

 Income Equity

  GINI index (log)2

World Bank, 2012

12%

1072.6 (269.17)

0.0001

0.35

–

 Access to Health Services and Commodities

  Out of pocket expenditure as % of total health expenditure (log)

WHO, 2013

0.06%

−23.7 (75.81)

0.7544

−0.02

–

  Physician density per 1000 population (log)

WHO, 2003–2013

10%

− 177.1 (47.11)

0.0003

− 0.32

–

 

Intermediate II Model R2:

62%

  1. Note: variables significant at p < 0.20 in bivariate analysis were entered into elastic net linear regression models; 1 Government effectiveness and corruption were strongly collinear (> 80%) and thus only the former was entered into multivariable modeling; 2 Due to small sample size (n = 117 countries), GINI index not considered in multivariable analysis; 1 GDP per capita and health expenditure per capita were strongly collinear (> 80%) and thus only the latter was entered into multivariable modeling
  2. a Level 3 multivariable model includes all statistically significant (p < 0.15) distal variables as listed
  3. b Level 2 multivariable model includes level 3 model+ all statistically significant (p < 0.15) intermediate I variables as listed
  4. c Level 1 multivariable model includes level 2 model+ all statistically significant (p < 0.15) intermediate II variables as list