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Table 2 Time-varying multivariate Cox regression model assessing the effect of intervention and mothers receiving infant’s HIV PCR test results on the hazard of maternal and infant non-retention in the study

From: Receipt of infant HIV DNA PCR test results is associated with a reduction in retention of HIV-exposed infants in integrated HIV care and healthcare services: a quantitative sub-study nested within a cluster randomised trial in rural Malawi

Parameter

Test

Infant

Mother

  

Hazard ratio (95%CI)

P-value

Hazard ratio (95%CI)

P-value

Receiving HIV test result (n = 682)d

HIV result given to mother (at any time)

1.70 (1.30,2.30)

< 0.001

1.30 (0.93,1.80)

0.118

Study arm

MIPa vs SOCb

0.87 (0.60,1.30)

0.445

0.99 (0.64,1.60)

0.932

MIP + SMSc vs SOC

0.71 (0.49,1.00)

0.075

0.94 (0.61,1.40)

0.769

Sex (child)

Female

1.10 (0.84,1.30)

0.620

1.10 (0.83,1.31)

0.655

Parity

No. children

0.98 (0.91,1.00)

0.320

0.98 (0.91,1.11)

0.574

Marital status

Single

Ref.

Ref.

Ref.

Ref.

Married

1.20 (0.63,2.40)

0.558

1.60 (0.69,3.70)

0.274

Widowed

0.59 (0.03,11.0)

0.724

4.20 (0.48,38.0)

0.196

Divorced

1.20 (0.43,3.30)

0.744

1.1 (0.31,3.81)

0.911

Education levele

None

Ref.

Ref.

Ref.

Ref.

Some primary

0.94 (0.74,1.20)

0.582

0.82 (0.66,1.00)

0.069

Completed primary

0.75 (0.40,1.40)

0.385

0.38 (0.16,0.92)

0.033

Some secondary

0.82 (0.46,1.50

0.506

0.78 (0.49,1.20)

0.297

Completed secondary

1.97 (0.41,2.30

0.953

0.72 (0.29,1.80)

0.472

Distance to the clinic

Less than 2 km 2-5 km

Ref. 0.95 (0.69,1.30)

Ref. 0.759

Ref. 0.95 (0.73,1.20)

Ref. 0.692

> 5 km

1.00 (0.74,1.40)

0.886

0.89 (0.67,1.20)

0.395

Mode of transport

Walking

Ref.

Ref.

Ref.

Ref.

Bus

0.96 (0.62,1.50)

0.843

1.35 (0.88, 1.90)

0.195

Taxi

0.50 (0.06,4.10)

0.521

0.85 (0.24,3.10)

0.802

Motorbike

1.20 (0.81,1.90)

0.325

0.99 (0.54,1.80)

0.988

Other

1.70 (0.77,3.70)

0.195

2.20 (0.82,5.90)

0.115

Mother on ART prior to study

No, newly initiated

Ref.

Ref.

Ref.

Ref.

No, not known

0.64 (0.37,1.10)

0.102

0.64 (0.33,1.20)

0.191

Yes

0.65 (0.49,0.85)

0.002

0.80 (0.64,0.99)

0.043

  1. aMother-and-infant clinics
  2. bStandard of care
  3. cMother-and-infant clinics with short messaging service
  4. dThe mother receiving the HIV PCR test result was treated as a time-varying covariate
  5. eThe number of mothers with greater than secondary education was too small to estimate the hazard ratio
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BMC Public Health

ISSN: 1471-2458

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