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Table 3 Multivariate Cox Proportional Hazard Model Adjusted for CRP

From: Income, inflammation and cancer mortality: a study of U.S. National Health and Nutrition Examination Survey mortality follow-up cohorts

Characteristics NHANES III 1988–1994 NHANES 1999–2002
Hazard Ratio 95% Confidence Interval P-value Hazard Ratio 95% Confidence Interval P-value
C-Reactive Protein (mg/dL)
  < 0.22 mg/dLa 1    1   
 0.22–0.99 mg/dL 1.01 0.81–1.26 0.90 0.94 0.55–1.59 0.80
  > 0.99 mg/dL 1.49 1.04–2.13 0.03 1.49 0.92–2.42 0.10
Race/Ethnicity
 Whitea 1    1   
 Black 1.25 0.97–1.61 0.09 1.29 0.75–2.23 0.35
 Hispanics/Other 0.90 0.61–1.34 0.61 1.30 0.64–2.64 0.46
Gender
 Malea 1    1   
 Female 0.68 0.54–0.87 0.003 0.52 0.27–0.99 0.047
Education
 Below High Schoola 1    1   
 High School/Equivalent 1.31 0.99–1.72 0.06 1.19 0.57–2.52 0.63
 Above High School 1.17 0.79–1.74 0.41 0.73 0.31–1.68 0.44
Income Level
 Lowa 1    1   
 Middle 0.85 0.70–1.05 0.12 1.20 0.70–2.05 0.49
 High 0.79 0.56–1.11 0.17 1.58 0.78–3.19 0.20
Occupation
 Blue Collar, Semi-Routinea 1    1   
 White Collar and Professional 0.89 0.60–1.32 0.54 0.73 0.40–1.31 0.28
 White Collar, Semi-Routine 0.94 0.60–1.46 0.76 1.04 0.57–1.91 0.89
 Blue Collar, High Skill 1.05 0.67–1.62 0.84 1.31 0.88–1.97 0.18
 Not Working 1.34 0.78–2.30 0.28 0.91 0.26–3.11 0.87
Body Mass Index (kg/m2)
 Underweighta 1    1   
 Normal 1.40 0.73–2.67 0.31 1.71 0.33–8.86 0.51
 Overweight 1.10 0.61–1.99 0.74 1.91 0.41–8.81 0.40
 Obese 1.64 0.84–3.17 0.14 2.58 0.52–12.72 0.24
Smoking
 Nevera 1    1   
 Former 1.67 1.15–2.42 0.01 2.23 1.32–3.77 0.004
 Current 3.86 2.87–5.18 < 0.001 6.99 4.11–11.88 < 0.001
Physical Activityb
 About the Samea 1    1   
 Less Active 1.15 0.86–1.53 0.35 1.15 0.57–2.32 0.68
 More Active 0.69 0.55–0.85 0.001 0.87 0.47–1.62 0.65
  1. a Reference group
  2. b Physical activity compared to others of same age