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Table 4 Results of one-way deterministic sensitivity analyses on the lifetime cost per QALY gained

From: Lifetime cost-effectiveness and equity impacts of the Healthy Primary School of the Future initiative

Time period

Parameters

Healthcare perspective

Societal perspective

 

PAS vs control schools

HPSF vs control schools

 

Reference scenario (deterministic results: Total net cost / Total QALYs gained)

€58,698

€19,734

  

lower

upper

lower

upper

Childhood & adolescence

Two-year intervention effects (+/− 20%)

€57,581

€59,619

€19,319

€20,061

Effect maintenance factors (+/− 20%)

€51,934

€62,020

€17,782

€20,977

Intervention costs (+/− 20%)

€48,807

€68,588

€16,150

€23,317

HRQOL weights (+/− 20%)

€57,546

€59,897

€19,338

€20,146

Ratio of HC costs for overweight and obesity vs. normal weight (+/− 20%)

€58,649

€58,747

€19,683

€19,784

Ratio of school absenteeism days for overweight and obesity vs. normal weight (+/− 20%)

 

€19,599

€19,868

HRQOL based on the quasi-experimental study a

 

€60,612

 

€20,390

Ratio of HC costs for overweight and obesity vs. normal weight based on the quasi-experimental study

€58,603

 

€19,637

 

Ratio of school absenteeism days for overweight and obesity vs. normal weight based on the quasi-experimental study

  

€19,756

Adulthood

HRQOL determined by weight category instead of by chronic disease in adulthood

€36,397

 

€12,273

 
 

Sick leave days for overweight and obesity vs. normal weight (+/− 20%)

 

€18,285

€25,779

 

Time horizon until age 70 years

 

€156,646

 

€79,523

 

Inclusion on short-term intervention costs (year 1 and 2) instead of estimated long-run costs only

 

€67,423

 

€32,649

 

Discount rates of 3% for both costs and effects

 

€183,687

 

€31,230

  1. Notes: HPSF the Healthy Primary School of the Future, PAS the Physical Activity School
  2. Costs discounted at 4% and effects discounted at 1.5% per year
  3. a We found no overall trend in utility decrements for overweight and obesity in the quasi-experimental study. Brown et al. (2018) also report that evidence on utility decrements in young children is inconclusive. No utility decrements were applied during the primary school period