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Table 4 Results of one-way deterministic sensitivity analyses on the lifetime cost per QALY gained

From: Lifetime cost-effectiveness and equity impacts of the Healthy Primary School of the Future initiative

Time period Parameters Healthcare perspective Societal perspective
  PAS vs control schools HPSF vs control schools
  Reference scenario (deterministic results: Total net cost / Total QALYs gained) €58,698 €19,734
   lower upper lower upper
Childhood & adolescence Two-year intervention effects (+/− 20%) €57,581 €59,619 €19,319 €20,061
Effect maintenance factors (+/− 20%) €51,934 €62,020 €17,782 €20,977
Intervention costs (+/− 20%) €48,807 €68,588 €16,150 €23,317
HRQOL weights (+/− 20%) €57,546 €59,897 €19,338 €20,146
Ratio of HC costs for overweight and obesity vs. normal weight (+/− 20%) €58,649 €58,747 €19,683 €19,784
Ratio of school absenteeism days for overweight and obesity vs. normal weight (+/− 20%)   €19,599 €19,868
HRQOL based on the quasi-experimental study a   €60,612   €20,390
Ratio of HC costs for overweight and obesity vs. normal weight based on the quasi-experimental study €58,603   €19,637  
Ratio of school absenteeism days for overweight and obesity vs. normal weight based on the quasi-experimental study    €19,756
Adulthood HRQOL determined by weight category instead of by chronic disease in adulthood €36,397   €12,273  
  Sick leave days for overweight and obesity vs. normal weight (+/− 20%)   €18,285 €25,779
  Time horizon until age 70 years   €156,646   €79,523
  Inclusion on short-term intervention costs (year 1 and 2) instead of estimated long-run costs only   €67,423   €32,649
  Discount rates of 3% for both costs and effects   €183,687   €31,230
  1. Notes: HPSF the Healthy Primary School of the Future, PAS the Physical Activity School
  2. Costs discounted at 4% and effects discounted at 1.5% per year
  3. a We found no overall trend in utility decrements for overweight and obesity in the quasi-experimental study. Brown et al. (2018) also report that evidence on utility decrements in young children is inconclusive. No utility decrements were applied during the primary school period