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Table 3 Contributing factors for intent to spontaneously report on adverse drug reactions (n = 1000)

From: A cross-sectional survey of knowledge, attitude, and willingness to engage in spontaneous reporting of adverse drug reactions by Korean consumers

Characteristics

Intent to spontaneously report ADRs, n (%)

Crude OR (95% CI)

aOR (95% CI)a

No (n = 408)

Yes (n = 592)

Demographic and clinical characteristics

 Sex

 Male

200

309

1.136 (0.882–1.462)

1.477 (1.104–1.976)**

 Female

208

283

1.0

1.0

 Age group

 Under 40 years

157

223

1.0

1.0

 40–65 years

212

320

1.063 (0.813–1.389)

1.065 (0.774–1.466)

 Over 65 years

39

49

0.885 (0.554–1.412)

1.012 (0.582–1.760)

 Residential area, n (%)

 Metropolitan area

184

266

0.993 (0.771–1.28)

0.938 (0.703–1.251)

 Rural area

224

326

1.0

1.0

 Level of education

 Low (less than high school graduate)

132

123

1.0

1.0

 High (more than university attendee)

276

469

1.824 (1.368–2.430)***

1.376 (0.980–1.932)

 Average monthly incomeb

 Low

220

246

1.0

1.0

 High

188

346

1.646 (1.276–2.122)***

1.427 (1.074–1.896)*

 Continuous medication

 No

177

238

1.0

1.0

 Yes

231

354

1.330 (0.976–1.812)

0.947 (0.651–1.378)

 Recent medication within one year

 No

71

63

1.0

1.0

 Yes

337

529

1.769 (1.227–2.550)**

1.439 (0.927–2.235)

 Have HCPs as family members or relatives

 No

389

558

1.0

1.0

 Yes

19

34

1.280 (0.956–1.715)

0.899 (0.641–1.262)

 Number of experiences related to ADRs

 ≤ 3 items

276

291

1.0

1.0

 4–5 items

132

301

2.163 (1.663–2.812)***

1.778 (1.327–2.381)***

Knowledge and attitude variables

 Amount of accurate knowledge on ADRs

 ≤ 4 items

244

282

1.0

1.0

 5 items

164

310

1.636 (1.267–2.111)***

1.304 (0.968–1.755)

 Awareness of SR system

 No

372

484

1.0

1.0

 Yes

36

108

2.306 (1.545–3.442)***

1.348 (0.811–2.240)

 Awareness of relief scheme for ADRs

 No

386

510

1.0

1.0

 Yes

22

82

2.821 (1.73–4.599)***

2.102 (1.233–3.584)**

 Self-efficacy of SR

 0–1 item

247

231

1.0

1.0

 2 items

161

361

2.397 (1.852–3.104)***

1.956 (1.467–2.609)***

 Number of positive attitude items on expectations of SR

 ≤ 2 items

231

185

1.0

1.0

 3 items

177

407

2.871 (2.210–3.730)***

2.027 (1.521–2.703)***

 Positive attitude on necessity and duty for SR

 No

188

92

1.0

1.0

 Yes

220

500

4.644 (3.456–6.240)***

3.972 (2.896–5.449)***

 Concerns on the barriers related to the detection of ADRs

 ≤ 2 items

181

318

0.687 (0.533–0.885)**

0.978 (0.720–1.330)

 3 items

227

274

1.0

1.0

 Concerns on the barriers derived from personal thoughts on the SR system

 ≤ 3 items

182

291

0.833(0.647–1.073)

1.076 (0.797–1.454)

 4–5 items

226

301

1.0

1.0

  1. aMultivariate analysis adjusted for all variables listed in the table
  2. b1st quintile (highest) to 3rd quintile of the average monthly income were categorised as a high-income group
  3. *p < 0.05, **p < 0.01, ***p < 0.001
  4. ADRs Adverse drug reactions, CI Confidence interval, HCPs Healthcare professionals, aOR Adjusted odds ratio, SR Spontaneous reporting