Incidence and risk factors of symptomatic knee osteoarthritis among the Chinese population: analysis from a nationwide longitudinal study

Table 3 Longitudinal analysis of incident symptomatic knee OA with different variables in different models

Variables	Model 1		Model 2
Variables	OR	95%CI	OR	95%CI
Gender
Male
Female	1.97	1.65–2.37	1.98	1.65–2.37
Age, years
< 50
50–59	0.88	0.60–1.28	0.88	0.60–1.29
60–69	1.18	0.82–1.71	1.14	0.78–1.64
≥ 70	1.09	0.76–1.57	1.01	0.70–1.47
Area
Urban
Rural	1.31	1.08–1.59	1.32	1.08–1.60
Region
East
Central	1.56	1.24–1.97	1.49	1.19–1.87
West	2.39	1.92–2.99	2.33	1.89–2.87
Education
No formal education
Elementary school	1.14	0.93–1.38	1.08	0.89–1.32
Middle school	0.70	0.54–0.92	0.69	0.52–0.90
High school or Vocational school or higher	0.64	0.43–0.93	0.60	0.41–0.88
BMI group (kg/m²)
< 18.5
18.5–24.9	1.08	0.79–1.47	1.10	0.80–1.51
≥ 25.0	1.25	0.89–1.75	1.21	0.87–1.69
Done some activities (such as played a sport, social, or other kind of club dancing, doing physical exercise, doing Qigong,et al.)
No
Yes	0.50	0.31–0.81	0.47	0.29–0.76
Chronic disease
Hypertension (Yes vs. No)			1.12	0.92–1.37
Dyslipidemia (Yes vs. No)			1.07	0.75–1.52
Diabetes (Yes vs. No)			1.30	0.78–2.14
Chronic lung disease (Yes vs. No)			1.19	0.92–1.55
Liver disease (Yes vs. No)			1.22	0.83–1.80
Heart disease (Yes vs. No)			1.40	1.07–1.82
Stroke (Yes vs. No)			1.67	0.97–2.86
Kidney disease (Yes vs. No)			1.80	1.35–2.39
Digestive disease (Yes vs. No)			1.54	1.30–1.82
Psychiatric disease (Yes vs. No)			1.07	0.60–1.90
Asthma (Yes vs. No)			1.17	0.75–1.81

Note: In model 1, we validated some known risk factors, including gender, age, area, region, education, BMI group, doing physical activities in the last month. In model 2, we explored additional potential risk factors, including histories of hypertension, dyslipidemia, diabetes, chronic lung disease, liver disease, heart disease, stroke, kidney disease, digestive disease, psychiatric disease, and asthma

ISSN: 1471-2458