Table 1 Socio-demographic and clinical characteristics of drug-resistant tuberculosis patients in Amhara region hospitals (n = 432)
Characteristics | Category | Frequency (%) |
|---|---|---|
Age in years | ≤24 | 142 (32.8) |
25–34 | 136 (31.5) | |
35–44 | 82 (19) | |
≥45 | 72 (16.7) | |
Level of education | No formal education | 186 (43) |
Primary school | 132 (30.6) | |
Secondary school | 75 (17.4) | |
Diploma and above | 39 (9) | |
Housing condition | Homeless | 19 (4.4) |
Had housing | 413 (96.4) | |
Occupation | Unemployed | 171 (39.6) |
Government employed | 39 (9) | |
Private | 187 (43.5) | |
Student | 35 (8.1) | |
Has treatment supporter | Yes | 367 (85) |
No | 65 (15) | |
HIV confection | Yes | 319 (73.8) |
No | 113 (26.2) | |
Diagnostic methods | GeneXpert Assay | 203 (47) |
LPA | 157 (36.3) | |
Culture and DST | 64 (8) | |
Clinically | 16 (3.7) | |
Baseline culture result (n = 430) | Positive | 352 (81.5) |
Negative | 20 (4.6) | |
Unknown | 60 (13.9) | |
Registration group | New | 57 (13.2) |
Previously treated | 375 (86.8) | |
Functional status at admission | Working | 47 (10.9) |
Ambulatory | 304 (70.4) | |
Bed ridden | 81 (18.7) | |
Body mass index (BMI) baseline | Low | 115 (26.6) |
Normal | 313 (72.5) | |
Overweight | 4 (0.9) | |
Base line Hgb in g/dl | < 7 g/dl | 11 (2.5) |
7–9.9 | 49 (11.3) | |
10–12.9 | 143 (33.1) | |
> = 13 | 148 (34.3) | |
Unknown | 81 (18.8) | |
Adverse drug effects (ADE) | Yes | 307 (71.1) |
No | 125 (28.9) | |
Drug side effects (n = 307) | Gastro-intestinal upset | 240 (78.2) |
Electrolyte disturbance | 105 (34.2) | |
Nephrotoxicity | 25 (8.1) | |
Psychosis | 40 (13) | |
Arthralgia | 74 (24.1) | |
Neuropathy | 19 (6.2) | |
Ototoxicity | 8 (2.6) | |
Others | 14 (4.5) | |
Radiological findings | Cavitation | 181 (41.9) |
Infiltrations | 115 (26.6) | |
Consolidations | 78 (18.1) | |
Chronic changes | 107 (24.8) | |
Others* | 57 (13.2) |