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Table 5 Factors associated with tuberculosis treatment success

From: Tuberculosis treatment outcomes: a fifteen-year retrospective study in Jos-North and Mangu, Plateau State, North - Central Nigeria

Variable

Treatment Outcome rate

COR (95% CI)

p (COR)

AOR (95%CI)

p (AOR)

Unsuccessful

n = 3299

Freq. (%)

Successful

n = 6856

Freq. (%)

Gender

 Male

1998 (60.6)

3906 (57.0)

Reference

 

Reference

 

 Female

1301 (39.4)

2950 (43.0)

1.160 (1.066–1.262)

0.010

1.161 (1.063–1.269)

0.001

Age

Not Recorded

877 (26.6)

886 (12.9)

Reference

 

Reference

 

 < 15 years

243 (7.4)

353 (5.1)

1.438 (1.191–1.736)

0.001

1.289 (1.061–1.567)

0.011

 > 15 years

2179 (66.1)

5617 (81.9)

2.552 (2.296–2.836)

0.001

1.819 (1.609–2.057)

0.001

Enrollment Year

 2001–2005

1121 (34.0)

1114 (16.2)

Reference

 

Reference

 

 2006–2010

1082 (32.8)

2816 (41.1)

2.619 (2.349–2.919)

0.001

1.646 (1.435–1.889)

0.001

 2011–2015

1096 (33.2)

2926 (42.7)

2.686 (2.411–2.993)

0.001

1.255 (1.060–1.486)

0.009

TB Diagnosis

 PTB

3025 (91.7)

6361 (92.8)

Reference

 

Reference

 

 EPTB

274 (8.3)

495 (7.2)

0.859 (0.737–1.002)

0.053

0.717 (0.611–0.841)

< 0.001

HIV Status

 Negative

919 (27.9)

2814 (41.0)

2.639 (2.388–2.917)

0.001

1.848 (1.593–2.143)

< 0.001

 Positive

781 (23.7)

2187 (31.9)

2.414 (2.172–2.683)

0.001

1.621 (1.394–1.885)

< 0.001

 Unknown

1599 (48.5)

1855 (27.1)

Reference

 

Reference

 

TB Category

 Transfer-In

40 (1.2)

124 (1.8)

Reference

   

 New

3063 (92.8)

6409 (93.5)

0.675 (0.471–0.966)

0.032

  

 RAD/TALF

86 (2.6)

132 (1.9)

0.495 (0.316–0.775)

0.002

  

 Relapse

99 (3.0)

183 (2.7)

0.596 (0.387–0.919)

0.019

  

 Trt. Failure

11 (0.3)

8 (0.1)

0.235 (0.088–0.624)

0.004

  

Needing Retreatment

 No

2459 (74.5)

6513 (95.0)

Reference

   

 Yes

180 (5.5)

342 (5.0)

0.717 (0.595–0.864)

0.001

  

 Indeterminate+

660 (20.0)

1 (0.0)

0.001 (0.000–0.004)

0.001

  

Adherent

 No

3296 (99.9)

15 (0.2)

0.001 (0.000 > 1.0E12)

0.999

  

 Yes

3 (0.1)

6842 (99.8)

Reference

   
  1. COR Crude Odds Ratio, AOR Adjusted Odds Ratio, Trt Treatment, PTB Pulmonary TB, EPTB Extrapulmonary TB, RAD Return after Default, TALF Treatment after lost to follow up, + Indeterminate due to lost to follow-up or death during intensive phase of treatment