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Table 5 Factors associated with tuberculosis treatment success

From: Tuberculosis treatment outcomes: a fifteen-year retrospective study in Jos-North and Mangu, Plateau State, North - Central Nigeria

Variable Treatment Outcome rate COR (95% CI) p (COR) AOR (95%CI) p (AOR)
Unsuccessful
n = 3299
Freq. (%)
Successful
n = 6856
Freq. (%)
Gender
 Male 1998 (60.6) 3906 (57.0) Reference   Reference  
 Female 1301 (39.4) 2950 (43.0) 1.160 (1.066–1.262) 0.010 1.161 (1.063–1.269) 0.001
Age
Not Recorded 877 (26.6) 886 (12.9) Reference   Reference  
 < 15 years 243 (7.4) 353 (5.1) 1.438 (1.191–1.736) 0.001 1.289 (1.061–1.567) 0.011
 > 15 years 2179 (66.1) 5617 (81.9) 2.552 (2.296–2.836) 0.001 1.819 (1.609–2.057) 0.001
Enrollment Year
 2001–2005 1121 (34.0) 1114 (16.2) Reference   Reference  
 2006–2010 1082 (32.8) 2816 (41.1) 2.619 (2.349–2.919) 0.001 1.646 (1.435–1.889) 0.001
 2011–2015 1096 (33.2) 2926 (42.7) 2.686 (2.411–2.993) 0.001 1.255 (1.060–1.486) 0.009
TB Diagnosis
 PTB 3025 (91.7) 6361 (92.8) Reference   Reference  
 EPTB 274 (8.3) 495 (7.2) 0.859 (0.737–1.002) 0.053 0.717 (0.611–0.841) < 0.001
HIV Status
 Negative 919 (27.9) 2814 (41.0) 2.639 (2.388–2.917) 0.001 1.848 (1.593–2.143) < 0.001
 Positive 781 (23.7) 2187 (31.9) 2.414 (2.172–2.683) 0.001 1.621 (1.394–1.885) < 0.001
 Unknown 1599 (48.5) 1855 (27.1) Reference   Reference  
TB Category
 Transfer-In 40 (1.2) 124 (1.8) Reference    
 New 3063 (92.8) 6409 (93.5) 0.675 (0.471–0.966) 0.032   
 RAD/TALF 86 (2.6) 132 (1.9) 0.495 (0.316–0.775) 0.002   
 Relapse 99 (3.0) 183 (2.7) 0.596 (0.387–0.919) 0.019   
 Trt. Failure 11 (0.3) 8 (0.1) 0.235 (0.088–0.624) 0.004   
Needing Retreatment
 No 2459 (74.5) 6513 (95.0) Reference    
 Yes 180 (5.5) 342 (5.0) 0.717 (0.595–0.864) 0.001   
 Indeterminate+ 660 (20.0) 1 (0.0) 0.001 (0.000–0.004) 0.001   
Adherent
 No 3296 (99.9) 15 (0.2) 0.001 (0.000 > 1.0E12) 0.999   
 Yes 3 (0.1) 6842 (99.8) Reference    
  1. COR Crude Odds Ratio, AOR Adjusted Odds Ratio, Trt Treatment, PTB Pulmonary TB, EPTB Extrapulmonary TB, RAD Return after Default, TALF Treatment after lost to follow up, + Indeterminate due to lost to follow-up or death during intensive phase of treatment