| WB | WB positive | ||||||
---|---|---|---|---|---|---|---|---|
Rate ratio | 95%CI | Â | P-value | Rate ratio | 95%CI | Â | P-value | |
Years | ||||||||
 2011 | Reference |  |  |  | Reference |  |  |  |
 2013 | 0.57 | 0.27 | 1.21 | 0.1435 | 0.87 | 0.66 | 1.14 | 0.3168 |
 2016 | 0.54 | 0.33 | 0.88 | 0.0145 | 0.59 | 0.45 | 0.77 | <.0001 |
Regions | ||||||||
 Hokkaido, Tohoku | 1.00 | 0.46 | 2.20 | 0.9982 | 0.30 | 0.22 | 0.40 | <.0001 |
 Kanto | 0.66 | 0.34 | 1.27 | 0.2140 | 0.29 | 0.22 | 0.39 | <.0001 |
 Chubu, Tokai | 0.88 | 0.36 | 2.12 | 0.7744 | 0.25 | 0.19 | 0.33 | <.0001 |
 Kinki | 0.85 | 0.46 | 1.59 | 0.6198 | 0.35 | 0.27 | 0.46 | <.0001 |
 Chugoku, Shikoku | 0.67 | 0.29 | 1.52 | 0.3385 | 0.27 | 0.21 | 0.36 | <.0001 |
 Kyusyu, Okinawa | Reference |  |  |  | Reference |  |  |  |
Units | ||||||||
 High-volume hospital | 0.63 | 0.36 | 1.08 | 0.0907 | 1.59 | 1.19 | 2.13 | 0.0019 |
 Middle- and low-volume hospital and clinic | Reference |  |  |  |  |  |  |  |