| Screening | Screening positive | ||||||
---|---|---|---|---|---|---|---|---|
Rate ratio | 95%CI | Â | P-value | Rate ratio | 95%CI | Â | P-value | |
Year | ||||||||
 2011 | Reference |  |  |  | Reference |  |  |  |
 2013 | 0.96 | 0.91 | 1.02 | 0.1781 | 0.74 | 0.42 | 1.30 | 0.2876 |
 2016 | 1.00 | 0.95 | 1.05 | 0.9242 | 0.69 | 0.38 | 1.27 | 0.2329 |
Regions | ||||||||
 Hokkaido, Tohoku | 1.20 | 1.04 | 1.37 | 0.0119 | 0.21 | 0.13 | 0.33 | <.0001 |
 Kanto | 0.55 | 0.48 | 0.62 | <.0001 | 0.30 | 0.17 | 0.52 | <.0001 |
 Chubu, Tokai | 0.77 | 0.68 | 0.87 | <.0001 | 0.43 | 0.17 | 1.06 | 0.0670 |
 Kinki | 0.89 | 0.79 | 1.02 | 0.0928 | 0.54 | 0.25 | 1.16 | 0.1142 |
 Chugoku, Shikoku | 1.33 | 1.15 | 1.53 | 0.0001 | 0.22 | 0.14 | 0.35 | <.0001 |
 Kyusyu, Okinawa | Reference |  |  |  | Reference |  |  |  |
Units | ||||||||
 High-volume hospital | 1.18 | 1.11 | 1.26 | <.0001 | 1.56 | 1.02 | 2.38 | 0.0386 |
 Middle- and low-volume hospitals and clinics | Reference |  |  |  |  |  |  |  |