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Table 1 Interview open-ended question guide

From: Recruitment, experience, and retention among women with HIV and hazardous drinking participating in a clinical trial

I. Drinking History
A. Tell me about your experience with drinking alcohol
1. At what age did you first start drinking?
2. When you first started drinking, were you a light, moderate, or heavy drinker?
3. Why did you decide to start drinking?
a. Traumatic experience, social drinker, stress, anxiety, depression …
4. What was it about alcohol that made you continue to drink?
5. Have you tried to quit drinking?
b. Tell me about your previous attempts to quit
i. Successful or Unsuccessful
ii. Time period that you were able to quit or reduce your drinking
iii. Were there any barriers that stopped you from quitting or reducing drinking?
II. Study Participation*
A. How did you find out about the study?
1. What was it about the study that motivated you to participate?
2. Tell me about your participation in other research studies, if any?
B. What benefits do you get out of participating in research?
C. Tell me about your experience in this study
1. What were some things that you like about the study?
2. What were some things that you did not like about the study?
a. What was difficult?
D. Describe your relationship with the study staff
1. What did you like about the study staff?
2. What did you not like about the study staff?
III. Changes as a result of participating in the WHAT-IF study
A. What changed in your life as a result of being in the study?
1. How were you able to quit or reduce drinking?
a. If so, why do you believe you were successful in doing so?
i. Do you think that the study medication helped to reduce or not reduce your drinking?
ii. Do you know if you were taking naltrexone or the placebo?
b. If not, why do you believe you were unsuccessful?
2. Besides drinking, what else changed in your life as a result of being in the study?
B. What do you think are the barriers (things that keep you from doing something) or the facilitators (things that help you do something) to this treatment that would exist in the real world outside of a research setting?
IV. Support
A. Did you have any support from family, friends, etc.?
B. When you think of someone that is being supportive, what are they doing?
1. Before being in the study, who did you receive support from?
a. In what ways were they supportive or not supportive of you wanting to quit or reduce drinking?
2. During the study, who did you receive support from?
a. In what ways were they supportive or not supportive of you wanting to quit or reduce drinking?
3. After completing the study, who did you receive support from?
a. In what ways were they supportive or not supportive of you wanting to quit or reduce drinking?
C. How important do you think it is to have support?
1. Who do you think are your best providers of support?
a. Family, friends, healthcare providers, etc.?
2. Do you think that support is needed in order to successfully quit or reduce drinking?
a. Why or why not?
V. Next steps
A. Now that you have completed the study, what would you recommend the research staff do next?
1. What could be done differently in the study?
B. If you were going to give advice to women about quitting or reducing their drinking, what would you tell them?
C. Additional information:
1. Would you like to add anything else?
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