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Table 3 Combined effects of benzene exposure on MN frequency, SCE frequency and T DNA% before and after publication bias correction by the trim and fill method

From: Occupational benzene exposure and the risk of genetic damage: a systematic review and meta-analysis

Genetic damage index The number of groups Q-value P-value Effect model SMD (95%CI)
Before trim, and fill After trim, and fill
MN frequency 49 49 1126.549 < 0.05 Random 1.36 (1.08–1.63)
SCE frequency 21 21 228.207 < 0.05 Random 0.98 (0.6–1.36)
T DNA% 5 6 113.919 < 0.05 Random 1.15 (0.37–1.91)