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Table 3 Factors associated with having at least one AGE episode during a winter season (univariate and multivariate analysis) among the 8811 participants-season, using the AGE definition of the French Sentinelles network

From: Determinants and risk factors of gastroenteritis in the general population, a web-based cohort between 2014 and 2017 in France

     univariate analysis multivariate analysis
Variable   N* Case N (%) OR [IC 95%] p-value OR [IC 95%] p-value
Season 2014–2015 3905 385 (10%) < 0.001 < 0.001
2015–2016 4906 412 (8%) 0.83 [0.72–0.95]   0.84 [0.73–0.97]  
2016–2017 5164 311 (6%) 0.58 [0.50–0.67]   0.56 [0.48–0.65]  
Sociodemographic characteristics
Gender Female 8381 663 (8%) 0.890   
Male 5594 445 (8%) 1.01 [0.88–1.15]    
Age (years) 15 to 59 7171 617 (9%) < 0.001 < 0.001
<  10 461 54 (12%) 1.42 [1.04–1.93]   1.26 [0.86–1.85]  
10 to 14 347 16 (5%) 0.52 [0.32–0.84]   0.60 [0.37–0.98]  
≥ 60 5978 420 (7%) 0.80 [0.70–0.92]   0.76 [0.64–0.89]  
Household composition Living with adults only 7266 536 (7%) 0.023 0.015
Living alone 2217 208 (9%) 1.28 [1.07–1.54]   1.31 [1.09–1.59]  
Living with ≥1 child 4443 361 (8%) 1.10 [0.95–1.28]   0.98 [0.82–1.17]  
Main activity Working 6595 573 (9%) 0.009   
Student 1287 91 (7%) 0.79 [0.62–1.01]    
Unemployed 370 34 (9%) 1.07 [0.72–1.60]    
Retired 4959 343 (7%) 0.77 [0.67–0.90]    
Stay at home/Sick leave 506 36 (7%) 0.82 [0.56–1.20]    
Level of education High school diploma 2564 211 (8%) 0.545   
Middle school diploma 2211 157 (7%) 0.86 [0.68–1.09]    
Higher education 7488 661 (8%) 0.99 [0.83–1.18]    
Not concerned 961 77 (8%) 0.99 [0.74–1.31]    
Place of residency Rural 2696 198 (7%) 0.269   
Urban 11,279 910 (8%) 1.10 [0.93–1.30]    
Exposure
Use of public transportation No 11,787 937 (8%) 0.876   
Yes 2188 171 (8%) 0.99 [0.83–1.18]    
Pets at home None 7689 552 (7%) < 0.001 < 0.001
At least one 6264 555 (9%) 1.26 [1.11–1.43]   1.23 [1.08–1.41]  
Contact with patients No 12,556 978 (8%)    
Yes 1424 130 (9%) 1.19 [0.98–1.44] 0.083   
Contact with elderly No 12,551 994 (8%)    
Yes 1424 114 (8%) 1.00 [0.81–1.23] 0.992   
Contact with a group of people No 9535 730 (8%)    
Yes 4440 378 (9%) 1.12 [0.98–1.28] 0.092   
Contact with children No 10,587 855 (8%)    
Yes 3388 253 (7%) 0.93 [0.80–1.08] 0.325   
Health characteristics
Common cold frequency Never 6076 399 (7%)   < 0.001
Rare 5031 399 (8%) 1.21 [1.04–1.40] < 0.001 1.17 [1.01–1.36]  
Often 2510 287 (11%) 1.79 [1.52–2.11]   1.63 [1.37–1.94]  
Smoking status Non smoker 12,466 973 (8%) 0.178   
Smoker 1493 133 (9%) 1.15 [0.94–1.41]    
Comorbiditiesa No comorbidities 10,987 810 (7%) < 0.001 < 0.001
At least one comorbidity 2988 298 (10%) 1.38 [1.19–1.60]   1.35 [1.16–1.58]  
Treated asthma 841 88 (10%) 1.37 [1.07–1.75] 0.012   
Treated diabetes 526 61 (12%) 1.53 [1.10–2.12] 0.011   
Treated heart condition 1400 133 (10%) 1.26 [1.04–1.53] 0.021   
Treated kidney condition 87 5 (6%) 0.69 [0.29–1.64] 0.396   
Treated immunosuppression 386 48 (12%) 1.67 [1.20–2.32] 0.023   
Treated pulmonary condition 365 34 (9%) 1.17 [0.82–1.69] 0.414   
Respiratory allergy None 9254 689 (7%) 0.008   
At least one 4721 419 (9%) 1.20 [1.05–1.37]    
BMI Normal weight (18.5 to 24[) 6923 560 (7%) < 0.001 < 0.001
Underweight (<  18.5) 1126 37 (6%) 0.84 [0.59–1.18]   0.72 [0.50–1.02]  
Overweight (25 to 29) 3340 318 (9%) 1.23 [1.05–1.43]   1.25 [1.07–1.45]  
Obese (≥ 30) 1347 171 (11%) 1.63 [1.33–1.99]   1.47 [1.19–1.81]  
  1. aWe only include the gathered variable “At least one comorbidity” in the final model, none of the individual one listed below