Model of genetic and environmental factors associated with type 2 diabetes mellitus in a Chinese Han population

BMC Public Health

Table 2 Associations of genetic models with risk of type 2 diabetes mellitus

SNP	Genotype	Unadjusted OR(95%CI)	Unadjusted P	Adjusted OR(95%CI)	Adjusted P
Rs5805
Additive	CT/TT	0.73(0.47 ~ 1.13)	0.155	0.71(0.46 ~ 1.10)	0.130
Additive	CC/ TT	0.34(0.10 ~ 1.09)	0.069	0.34(0.11 ~ 1.12)	0.077
Dominant	CC + CT/TT	0.67(0.44 ~ 1.02)	0.062	0.66(0.43 ~ 1.01)	0.050
Recessive	CC/CT + TT	0.39(0.12 ~ 1.23)	0.107	0.40(0.12 ~ 1.28)	0.120
Rs12654264
Additive	AT/AA	0.79(0.48 ~ 1.30)	0.347	0.81(0.49 ~ 1.35)	0.414
	TT/AA	0.45(0.24 ~ 0.84)	0.012	0.46(0.25 ~ 0.87)	0.017
Dominant	TT + AT/AA	0.66(0.41 ~ 1.06)	0.087	0.68(0.42 ~ 1.10)	0.512
Recessive	TT/AT+AA	0.53(0.32 ~ 0.90)	0.019	0.53(0.32 ~ 0.91)	0.021
Rs2065412
Additive	CT/TT	0.31(0.11 ~ 0.84)	0.022	0.31(0.11 ~ 0.86)	0.299
Additive	CC/TT	–	0.999	–	0.999
Dominant	CC + CT/TT	0.30(0.11 ~ 0.81)	0.018	0.73(0.48 ~ 1.10)	0.020
Recessive	CC/CT + TT	–	0.999	–	0.999
Rs4149336
Additive	CT/CC	0.59(0.37 ~ 0.92)	0.019	0.59(0.37 ~ 0.92)	0.021
Additive	TT/CC	0.53(0.25 ~ 1.14)	0.103	0.52(0.24 ~ 1.19)	0.094
Dominant	TT + CT/CC	0.57(0.38 ~ 0.87)	0.009	0.57(0.37 ~ 0.88)	0.010
Recessive	TT/CT + CC	0.68(0.32 ~ 1.41)	0.300	0.66(0.31 ~ 1.39)	0.271
Rs964184
Additive	CG/CC	1.31(0.84 ~ 2.03)	0.232	1.40(0.90 ~ 2.18)	0.140
Additive	GG/CC	2.24(0.99 ~ 5.09)	0.055	2.38(1.03 ~ 5.53)	0.043
Dominant	GG + CG/CC	1.41(0.93 ~ 2.13)	0.111	1.50(0.98 ~ 2.30)	0.060
Recessive	GG/CG + CC	2.21(0.91 ~ 4.52)	0.085	2.10(0.93 ~ 4.79)	0.076

Adjusted for waist circumference, the history of hypertension, the intake of meat, degree of education, exercise. The meaning of “/” is “VS”; the meaning of “+” is “and”

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