Early exposure to social disadvantages and later life body mass index beyond genetic predisposition in three generations of Finnish birth cohorts

Table 2 Descriptives by early social disadvantage in Helsinki Birth Cohort 1934–1944 (HBCS1934–1944), Northern Finland Birth Cohort 1966 (NFBC1966) and Northern Finland Birth Cohort 1986 (NFBC1986)

HBCS1934–1944 Early social disadvantage										NFBC1966 Early social disadvantage													NFBC1986 Early social disadvantage
	High			Intermediate			Low				High			Intermediate			Low					High		Intermediate			Low
	n	%		n		%	n	%			n	%		n		%	n		%			n	%	n	%		n	%
	398	31		561		44	318	25			1463	25		2900		50	1444		25			1682	25	3363	50		1672	25
	n	\( \overline{x} \)	sd	n	\( \overline{x} \)	sd	n	\( \overline{x} \)	sd	p.	n	\( \overline{x} \)	sd	n	\( \overline{x} \)	sd	n	\( \overline{x} \)	sd	p.	n	\( \overline{x} \)	sd	n	\( \overline{x} \)	sd	n	\( \overline{x} \)	sd	p.
BMI	398	28.2	5.5	561	27.4	4.5	318	27.7	4.3	0.046	1463	27.3	5.0	2900	26.8	4.9	1444	26.5	4.7	< 0.001	818	21.5	3.8	1625	21.4	3.7	779	21.0	3.1	0.014
Mat BMI	366	26.6	3.0	508	26.5	2.8	273	26.5	3.2	0.67	1276	23.7	3.5	2667	23.2	3.2	1398	22.6	2.7	< 0.001	818	22.5	3.7	1625	22.3	3.5	779	21.9	2.7	< 0.001
Sex	n	%		n		%	n	%		0.018	n	%		n		%	n		%	0.019		n	%	n	%		n	%		0.612
Men	176	31		236		41	165	29			619	42		1254		43	680		47			408	49.9	776	47.8		378	48.5
Women	222	31		325		46	153	22			844	58		1646		57	764		53			410	50.1	849	52.3		401	51.5

^aBMI was measured at age of approximately 62 years in HBCS1934–1944, 46 in NFBC1966 and 16 in the NFBC1986
^bMat BMI = maternal body mass index measured during late pregnancy in HBCS1934–1944
^cPRS BMI = in polygenic risk score for body mass index standardized values used

ISSN: 1471-2458