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Table 2 Demographic and Clinical Characteristics, Stratified by Incident Hypertension Status (N = 984)

From: Incidence of hypertension among persons living with HIV in China: a multicenter cohort study

Characteristic

No HTN(n = 807)

HTN (n = 177)

P value

Male

603 (74.7)

137 (77.4)

0.46

Age (years)

34.4 ± 9.4

38.8 ± 11.2

< 0.001

BMI (kg/m2)

21.3 ± 2.8

22.1 ± 3.1

< 0.01

 Overweight

72 (8.9)

21 (11.9)

0.23

 Obese

6 (0.7)

4 (2.3)

NA

Han ethnicity

676 (83.8)

157 (88.7)

0.10

Smoking

200 (24.8)

38 (21.5)

0.35

Current alcohol use

224 (27.8)

40 (22.6)

0.16

eGFR (ml/min)

114 ± 16

110 ± 19

< 0.01

 eGFR < 90 (ml/min)

62 (7.7)

21 (11.9)

0.07

Diabetes

40 (5.0)

9 (5.1)

0.95

TC > 5.2 (mmol/l)

81 (10.0)

21 (11.9)

0.48

TG > 1.7 (mmol/l)

229 (28.4)

54 (30.5)

0.59

HDL-c < 1.0 (mmol/l)

240 (29.7)

63 (35.6)

0.17

LDL-c > 4.1 (mmol/l)

11 (1.4)

3 (1.7)

NA

Dyslipidemia

397 (49.2)

100 (56.5)

0.15

HBs Ag+

88 (10.9)

22 (12.4)

0.51

HCV Ab+

50 (6.2)

19 (10.7)

0.03

Route of HIV transmission

  

< 0.001

 Heterosexual

339 (42.0)

61 (34.5)

 

 Homosexual

370 (45.8)

81 (45.8)

 

 Blood transfusion

23 (2.9)

22 (12.4)

 

 Others

75 (9.3)

13 (7.3)

 

Years since HIV diagnosis

1.0 ± 1.7

1.1 ± 1.8

0.36

Baseline CD4+ cell count (cells/mm3)

238 ± 125

206 ± 124

< 0.01

Baseline HIV Viral load

(log10 copies/ml)

4.7 ± 0.7

4.7 ± 0.7

0.52

Stavudine exposure

248 (30.7)

97 (54.8)

< 0.001

 Years of stavudine exposure

Zidovudine exposure

1.2 ± 1.1

316 (39.2)

0.6 ± 0.7

64 (36.2)

< 0.0010.46

 Years of zidovudine exposure

TDF exposure

3.3 ± 1.9

470 (58.2)

1.2 ± 1.1

54 (30.5)

< 0.001

< 0.001

 Years of TDF exposure

Recent CD4+ cell count (cells/mm3)

1.8 ± 0.7

453 ± 204

0.4 ± 0.5

330 ± 162

< 0.001

< 0.001

Recent CD4+/CD8+ ratio

0.7 ± 0.5

0.5 ± 0.3

< 0.001

Recent VL (log10 copies/ml)

1.5 ± 0.7

2.0 ± 0.7

< 0.001

  1. Values are shown as n (%) or mean ± standard deviation
  2. Abbreviations: HTN hypertension; BMI body mass index; NA not available; eGFR, estimated glomerular filtration rate; TC total cholesterol; TG triglycerides; HDL-c high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; HBsAg+, hepatitis B surface antigen; HCV-Ab hepatitis C antibody; HIV human immunodeficiency virus; VL HIV-1 viral load; TDF tenofovir disoproxil fumarate
  3. * Unless stated otherwise, characteristics reported represent baseline characteristics