Skip to main content

Table 5 Parameter effects (with 95% CI) of Socio-demographics variables, risk variables, HR-QoL domain scores and clinical measurements on length of stay (waiting time) for the CD4 based Weibull multistate Markov model

From: Modelling immune deterioration, immune recovery and state-specific duration of HIV-infected women with viral load adjustment: using parametric multistate model

Variables

Waiting in Normal

Waiting in Mild

Waiting in Advanced

Waiting in Severe

Exp(β)

(95% CI)

Exp(β)

(95% CI)

Exp(β)

(95% CI)

Exp(β)

(95% CI)

Orthogonal Viral load

0.90 (0.81, 0.99)***

1.42 (0.60, 3.33)

1.27 (1.11, 1.45)**

1.28 (1.15, 1.43)**

TB: Yes

1.18 (0.34, 4.19)

0.99 (0.76, 1.29)

1.08 (0.75, 1.56)

1.44 (0.63, 3.30)

Age_Cat: 18–20 years

0.56 (0.39, 1.80)

1.11 (0.77, 1.17)

1.16 (0.91, 1.48)

0.22 (0.11, 1.45)

Age_Cat: 21–39 years

2.31 (0.07, 4.96)

1.05 (0.78, 1.47)

0.74 (0.54, 1.02)

0.02 (0.01, 1.03)

Anemia: Yes

1.12 (0.97, 1.30)

1.05 (0.91, 1.21)

1.08 (0.89, 1.30)

0.87 (0.51, 1.49)

Education: Grade 9–10

3.56 (1.34, 9.48)*

1.07 (0.79, 1.45)

1.33 (0.92, 1.94)

0.94 (0.61, 1.45)

Education: Grade > 11

4.80 (2.02, 11.40)*

0.87 (0.67, 1.14)

1.23 (0.92, 1.65)

0.91 (0.58, 1.43)

Marital Status: Married/stable sexual partners

1.51 (1.01, 2.25)*

1.27 (1.01, 2.05)*

0.98 (0.56, 1.73)

1.18 (0.34, 3.91)

Marital Status: Single/no sexual partners

1.71 (1.14, 2.78)*

1.26 (0.98, 1.63)

0.82 (0.62, 1.08)

2.60 (0.17, 16.19)

Sex while Drunk: yes

1.08 (0.78, 1.50)

0.95 (0.71, 1.26)

1.05 (0.77, 1.44)

1.41 (0.88, 2.28)

RBC indices component

1.05 (0.99, 1.12)

0.99 (0.92, 1.06)

0.94 (0.86, 1.03)

1.17 (0.99, 1.39)

Hb and Haematocrit component

1.11 (1.04, 1.19)

1.00 (0.93, 1.07)

0.94 (0.86, 1.02)

1.26 (0.99, 1.61)

Granulocytes component

0.98 (0.93, 1.03)

0.93 (0.88, 1.99)

0.99 (0.92, 1.07)

0.88 (0.66, 1.18)

Mononuclear component

1.27 (1.18, 1.38)**

1.12 (1.04, 1.21)**

1.07 (0.99, 1.15)

0.86 (0.64, 1.16)

Liver enzymes abnormality component

1.01 (0.95, 1.06)

0.99 (0.93, 1.05)

1.02 (0.95, 1.08)

0.87 (0.65, 1.18)

Weight

1.00 (0.99, 1.00)

1.00 (0.99, 1.00)

1.00 (0.99, 1.00)

1.01 (0.98, 1.04)

Psychological well-being scores

0.89 (0.83, 1.00)

0.96 (0.79, 1.17)

0.88 (0.83, 0.94)**

0.87 (0.81, 0.93)*

Physical health scores

1.07 (1.01, 1.14)**

1.12 (1.05, 1.21)*

1.06 (0.99, 1.12)

0.85 (0.73, 0.99)**

Independence scores

1.00 (0.97, 1.03)

1.00 (0.97, 1.03)

0.98 (0.96, 1.01)

0.95 (0.88, 1.03)

Social relationship scores

0.97 (0.93, 1.00)

0.95 (0.92, 1.00)

0.97 (0.93, 1.00)

0.96 (0.87, 0.99)*

  1. Key:- Statistical significance: (*)P < 0.05; (**)P < 0.01; (***)P < 0.001; reference category: Age [> 40]; education [grade ≤ 8]; marital status [Many sexual partners]; TB [No]; Anemia [No]