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Table 1 Characteristics, benzene exposure levels, fat content, and erythroid-related hematologic parameters in workers in different workplaces

From: Influence of benzene exposure, fat content, and their interactions on erythroid-related hematologic parameters in petrochemical workers: a cross-sectional study

Variablesa

Control group (n = 338)

Exposed group (n = 1331)

P value

General characteristics

 Age (years)

46.46 ± 7.25

40.20 ± 7.37

< 0.001b

 Gender (male/female, %male)

237/101 (70.10)

1014/317 (76.20)

0.022c

 Smoking status (smoker/non-smoker, %smoker)

98/240 (29.00)

466/865 (35.00)

0.037c

 Drinking status (drinker/non-drinker, %drinker)

103/235 (30.50)

490/841 (36.80)

0.030c

 Work years (years)

25.94 ± 8.45

18.93 ± 8.52

< 0.001b

Benzene exposure levels

 SPMA (μg/g creatinine)

0.18 (0.09, 0.44)

0.37 (0.15, 1.09)

< 0.001d

Fat content indices

 BF% (%)

26.66 ± 5.29

23.67 ± 23.67

0.003e

 TC (mmol/L)

5.48 ± 0.94

5.20 ± 0.96

0.410d

 TG (mmol/L)

1.66 ± 1.11

1.59 ± 1.41

0.305d

 Fatty liver (yes/no, %yes)

84/250 (25.10)

311/1016 (23.40)

0.551c

Erythroid-related hematologic parameters

 RBC count (×1012/L)

4.94 ± 0.58

4.96 ± 0.58

0.157d

 Hb (g/L)

142.71 ± 13.93

143.60 ± 14.53

0.286d

 HCT (%)

42.62 ± 3.52

43.25 ± 4.07

0.027d

 MCV (fL)

86.90 ± 8.15

87.70 ± 8.17

0.030d

 MCHC (g/L)

336.87 ± 8.22

331.92 ± 10.53

< 0.001d

 RDW-CV (%)

12.90 ± 1.03

13.17 ± 1.36

0.792d

 RDW-SD (fL)

39.87 ± 2.57

43.86 ± 3.35

< 0.001d

  1. Abbreviations: SPMA S-phenylmercapturic acid, BF% Body fat percentage, TC Plasma total cholesterol, TG Plasma triglycerides, RBC Red blood cell, Hb Hemoglobin concentration, HCT Hematocrit, MCV Mean corpuscular volume, MCHC Mean corpuscular hemoglobin concentration, RDW-CV Red cell distribution width-coefficient of variation, RDW-SD Red cell distribution width-standard deviation
  2. a Values were shown by n (%), mean ± SD, or median (25th percentile, 75th percentile)
  3. b Student’s t-test
  4. c Chi-squared test
  5. d Multivariate analysis of covariance, adjusted by age, gender, smoking status, drinking status, and work years
  6. e Multivariate analysis of covariance, adjusted by smoking status, drinking status, and work years