Skip to main content

Advertisement

Table 1 Adjusted hazard ratios of mortality and AIDS-defining event for all patients enrolled at time of data audit using the pre-audit and post-audit datasets

From: The impact of data quality and source data verification on epidemiologic inference: a practical application using HIV observational data

 MortalityAIDS-defining event
Pre-Audit Hazard RatioPost-Audit Hazard RatioPre-Audit Hazard RatioPost-Audit Hazard Ratio
Gender
 FemaleRefRefRefRef
 Male1.08 (0.96, 1.21)1.04 (0.94, 1.15)0.88 (0.74, 1.04)0.93 (0.84, 1.04)
Age
 201.11 (0.87, 1.42)1.08 (0.87, 1.33)1.18 (0.90, 1.54)1.06 (0.86, 1.31)
 300.92 (0.82, 1.03)0.90 (0.82, 0.99)1.05 (0.93, 1.19)0.99 (0.89, 1.12)
 40RefRefRefRef
 501.30 (1.21, 1.40)1.36 (1.29, 1.44)0.97 (0.89, 1.05)1.04 (0.94, 1.15)
 601.77 (1.49, 2.11)1.96 (1.71, 2.26)0.94 (0.76, 1.17)1.09 (0.85, 1.39)
Clinical AIDS at baseline
 NoRefRefRefRef
 Yes2.07 (1.80, 2.39)1.64 (1.46, 1.84)7.55 (6.10, 9.34)2.04 (1.40, 2.99)
Nadir CD4
 501.90 (1.59, 2.27)1.96 (1.68, 2.28)1.31 (1.02, 1.70)1.87 (1.56, 2.25)
 1001.46 (1.24, 1.73)1.52 (1.32, 1.75)1.17 (0.94, 1.46)1.55 (1.32, 1.82)
 2001.05 (0.92, 1.19)1.11 (0.99, 1.23)0.98 (0.86, 1.13)1.14 (1.04, 1.24)
 350RefRefRefRef
Initiation Year
 20000.83 (0.70, 0.99)0.91 (0.79, 1.06)1.00 (0.83, 1.22)1.15 (0.92, 1.43)
 20020.85 (0.74, 0.97)1.01 (0.91, 1.13)0.94 (0.79, 1.13)1.08 (0.87, 1.34)
 20040.90 (0.82, 0.99)1.05 (0.97, 1.13)0.95 (0.87, 1.05)1.02 (0.90, 1.17)
 2006RefRefRefRef
 20081.07 (1.00, 1.15)0.98 (0.93, 1.04)1.04 (0.94, 1.14)1.04 (0.95, 1.14)
 20101.03 (0.84, 1.25)1.08 (0.93, 1.26)1.06 (0.85, 1.33)1.15 (0.96, 1.39)
 20120.94 (0.62, 1.42)1.27 (0.92, 1.74)1.09 (0.74, 1.59)1.30 (0.96, 1.77)
ARV CLASS
 NNRTIRefRefRefRef
 Boosted PI1.30 (1.08, 1.55)1.22 (1.04, 1.44)1.05 (0.88, 1.25)0.97 (0.83, 1.15)
 Other1.11 (0.91, 1.37)1.21 (1.02, 1.44)0.99 (0.80, 1.24)1.14 (0.88, 1.48)
IVDU
 NoRefRefRefRef
 Yes1.22 (0.81, 1.84)1.56 (1.01, 2.40)0.94 (0.70, 1.25)1.11 (0.89, 1.39)