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Table 2 Case burdens of different health responses. Case burden is calculated as the product of disease-specific disability weights and disease durations

From: Health effects of nutrients and environmental pollutants in Baltic herring and salmon: a quantitative benefit-risk assessment

Response

DALYs per case

Description

Tooth defect

0–0.12

disability weight 0.001 and duration 60 a (years) with 100% uncertainty. For comparison, IHME gives disability weight 0 for asymptomatic caries and 0.006 for mild other oral disorders with symptoms [43].

Cancer

19.7 (17.8–21.8)

based on breast cancer, from IHME [44]

Vitamin D intake

0.0001–0.01

disability weight 0.001 and duration 1 a with 100-fold log-uniform uncertainty

TWI 2001

0.0001–0.01

disability weight 0.001 and duration 1 a with 100-fold log-uniform uncertainty

TWI 2018

0.0001–0.01

disability weight 0.001 and duration 1 a with 100-fold log-uniform uncertainty

Infertility

0–5

disability weight 0.1 and duration 50 a with 100% uncertainty. See also text. Here we used a clearly higher disability weight than IHME (0.008) [43].

Child’s IQ

0.11 (95% CI 0.06–0.16)

Mild intellectual disability (IQ < 70) has disability weight 0.043 (95% CI 0.026–0.064) based on IHME [43]. This is scaled to one IQ point with duration 75 a.