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Table 2 Direct and indirect effects of leisure-time physical activity with lung function

From: C-reactive protein mediates the association between leisure-time physical activity and lung function in middle-aged and older adults

Lung function

Association

β (95%CI)

Mediation (%)a

FEV1

 PA-Moderate

  Total

0.085 (0.049, 0.121)

 

  Direct

0.077 (0.041, 0.113)

 

  Indirect via CRP

0.009 (−0.001, 0.017)

10.05

 PA-High

  Total

0.149 (0.106, 0.193)

 

  Direct

0.130 (0.086, 0.174)

 

  Indirect via CRP

0.019 (0.010, 0.029)

12.99b

FVC

 PA-Moderate

  Total

0.131 (0.086, 0.176)

 

  Direct

0.123(0.078, 0.168)

 

  Indirect via CRP

0.009 (−0.001, 0.017)

6.58

 PA-High

  Total

0.207 (0.153, 0.262)

 

  Direct

0.188 (0.133,0.243)

 

  Indirect via CRP

0.020 (0.010, 0.029)

9.42b

  1. CRP C-reactive protein, CI Confidence interval, FEV1 Forced expiratory volume in one second, FVC Forced vital capacity, PA Physical activity; β: regression coefficient
  2. Models were adjusted for age, sex, education level, cigarette smoking, alcohol drinking, body mass index, cardiovascular diseases (angina, congestive heart failure and stroke), chronic lung diseases, cancer and dementia
  3. Total effect is the effect of PA on lung function without CRP; direct effect is the effect of PA on lung function when controlling for CRP; indirect effect is the effect of PA on lung function via CRP
  4. aMediation (%) is calculated by indirect effect/total effect ×100
  5. bP<0.001
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BMC Public Health

ISSN: 1471-2458

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