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Table 2 Discrepancies in data found between ART and DR-TB registers in patients matched between data sources

From: Data quality of drug-resistant tuberculosis and antiretroviral therapy electronic registers in South Africa

 Site 1
(FIS/TE)
(n = 149)
Site 2
(EDRWeb/
TIER.NET)
(n = 340)
Site 3
(EDRWeb/
TIER.NET)
(n = 1449)
Total
(n = 1938)
Reporting of date of birth
 Agree92.6% (138)92.7% (315)88.3% (1279)89.4% (1732)
 Discrepant between DR-TB and ART register7.4% (11)7.4% (25)8.4% (121)8.1% (157)
 Missing in ART register0.0% (0)0.0% (0)0.1% (2)0.1% (2)
 Missing in DR-TB register0.0% (0)0.0% (0)3.2% (47)2.4% (47)
DR-TB treatment recorded in ART register
 Not recorded/missing3.4% (5)42.4% (144)1.4% (20)8.7% (169)
 Has not started TB treatment0.0% (0)2.7% (9)2.7% (39)2.5% (48)
 Started TB treatment96.6% (144)55.0% (187)95.9% (1390)88.8% (1721)
HIV status reported in DR-TB register
 Positive100% (149)93.8% (319)95.6% (1385)95.6% (1853)
 Negative0.0% (0)5.6% (19)2.6% (37)2.9% (56)
 Unknown or missing0.0% (0)0.6% (2)1.9% (27)1.5% (29)
ART status recorded in DR-TB register
 Not recorded/missing0.0% (0)1.5% (5)3.7% (53)3.0% (58)
 Has not started ART6.7% (10)5.6% (19)11.7% (169)10.2% (198)
 Started ART93.3% (139)92.9% (316)84.7% (1227)86.8% (1682)
Reporting of ART start date
 Not recorded in either register1.3% (2)0.0% (0)0.1% (2)0.2% (4)
 Recorded in ART register, but not DR-TB register6.7% (10)99.7% (339)80.5% (1167)78.2% (1516)
 Recorded in DR-TB register, but not ART register10.7% (16)0.0% (0)0.0% (0)0.1% (16)
 Recorded in both registers81.2% (121)0.3% (1)19.3% (280)20.7% (402)
  ART start dates agree32.2% (39/121)0.0% (0/1)84.6% (237/280)68.7% (276/402)
  ART start dates differ by ≤1 month17.3% (21/121)0.0% (0/1)5.4% (15/280)9.0% (36/402)
  ART start dates differ by > 1 month50.4% (61/121)100% (1/1)10.0% (28/280)22.4% (90/402)
Reporting of ART regimen
 Not recorded in either register8.1% (12)0.0% (0)0.0% (0)0.6% (12)
 Recorded in ART register, but not DR-TB register44.3% (66)100% (340)100% (1449)95.7% (1855)
 Recorded in DR-TB register, but not ART register3.4% (5)0.0% (0)0.0% (0)0.3% (5)
 Recorded in both registers44.3% (66)0.0% (0)0.0% (0)3.4% (66)
  ART regimens agree86.4% (57/66)N/AN/A86.4% (57/66)
Reporting of death and date of death
 No deaths in either register81.9% (122)84.4% (287)76.8% (1113)78.5% (1522)
 Death in ART register, but not DR-TB register2.7% (4)1.5% (5)4.0% (58)3.5% (67)
  Reported in DR-TB register as:
   Lost to follow-up353038
   Transferred out1001
   Cured0088
   Treatment completed0066
   Still on treatment0022
   Treatment failure0011
   Not specified001111
 Death in DR-TB register, but not ART register4.7% (7)2.9% (10)8.6% (124)7.3% (141)
  Reported in ART register as:
   Lost to follow-up08106114
   Transferred out321621
   Not specified4004
 Death in both registers10.7% (16)11.2% (38)10.6% (154)10.7% (208)
  Death dates agree25.0% (4/16)55.3% (21/38)59.1% (91/154)55.8% (116/208)
  Death dates differ by ≤1 month31.3% (5/16)39.5% (15/38)26.0% (40/154)28.8% (60/208)
  Death dates differ by > 1 month43.8% (7/16)5.3% (2/38)14.9% (23/154)15.4% (32/208)
Death reported in ART register prior to non-death outcome in DR-TB register0.0% (0)0.3% (1)1.5% (22)1.2% (23)
Death reported in DR-TB register prior to non-death outcome in ART register0.0% (0)0.9% (3)3.4% (49)2.7% (52)
Lost to follow-up in ART register, death recorded in DR-TB register within 3 months0.0% (0)1.8% (6)4.6% (66)3.7% (72)
Lost to follow-up in DR-TB register, death recorded in ART register within 3 months2.0% (3)0.9% (3)0.5% (7)0.7% (13)
Transferred out in ART register, death recorded in DR-TB register within 3 months0.7% (1)0.3% (1)0.4% (5)0.4% (7)
Transferred out in DR-TB register, death recorded in ART register within 3 months0.0% (0)0.0% (0)0.0% (0)0.0% (0)
  1. Abbreviations: DR-TB Drug resistant tuberculosis, ART Antiretroviral therapy, FIS Focal Point Information System, TE TherapyEdge-HIV™, EDRWeb Electronic Drug Register Web, TIER.NET The Three Integrated Electronic Registers
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