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Table 4 Survival submodel with slope parameterizations under Weibull accelerated failure time for DR-TB patients in Amhara region, Ethiopia

From: Time to poor treatment outcome and its predictors among drug-resistant tuberculosis patients on second-line anti-tuberculosis treatment in Amhara region, Ethiopia: retrospective cohort study

Variables

Status

Event (%)

Censored (%)

CTR[95% CI]

ATR[95% CI]

Age

  < =24

16 (9.7)

149 (90.3)

1.00

1.00

 25–44

45 (17.4)

213 (82.6)

0.42 [0.21 0.88]

0.45 [0.14 1.84]

 45 and above

25 (29.4)

60 (70.6)

0.18 [0.17 0.43]

0.28 [0.10 0.68]

Residence

 Urban

27 (11.1)

216 (88.9)

1.00

1.00

 Rural

59 (22.3)

206 (77.7)

0.36 [0.20 0.67]

0.51 [0.30 0.86]

TB complication

 Yes

52 (57.1)

39 (42.9)

1.00

1.00

 No

34 (8.2)

383 (91.8)

15 [7.59 29.72]

7.65 [4.22 13.88]

Sputum smear

 Positive

72 (18.0)

328 (82.0)

1.00

1.00

 Negative

14 (13.0)

94 (87.0)

1.56 [0.75 3.27]

1.23 [0.65 2.33]

Education

 No education

50 (22.0)

177 (78.0)

1.00

1.00

 Primary

24 (16.9)

118 (83.1)

1.47 [0.79 2.73]

0.75 [0.41 1.36]

 Secondary and above

12 (8.7)

127 (91.3)

3.87 [1.68 8.90]

2.34 [1.34 2.88]

Anemia

 Anemic

75 (24.1)

236 (75.9)

1.00

1.00

 Not anemic

11 (5.6)

186 (94.4)

3.37 [1.35 8.41]

2.58 [1.21 3.80]

HIV

 Positive

30 (24.4)

93 (75.6)

1.00

1.00

 Negative

56 (14.6)

329 (85.4)

2.15 [1.21 3.84]

1.94 [1.35 2.35]

Diabetes

 Yes

7 (43.7)

9 (56.3)

1.00

1.00

 No

79 (16.1)

413 (83.9)

4.52 [1.64 12.46]

3.45 [1.34 8.86]

TB treatment

 No treatment

9 (12.2)

65 (87.8)

1.00

1.00

 One and above

77 (17.7)

370 (82.3)

0.57 [0.22 1.49]

0.37 [0.16 0.86]

Smoking history

 Yes

18 (25.7)

52 (74.23

1.00

1.00

 No

68 (15.5)

370 (84.5)

2.05 [1.04 4.02]

1.29 [1.07 2.88]

  1. CTR Crude time ratio, ATR Adjusted time ratio, TB tuberculosis, TB complication (pneumonia, hemoptysis, pneumothorax, Corpulmonale