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Table 2 Temporal trends in cause-specific deaths by county of residency at time of death (San Francisco County vs. all other counties), among people diagnosed with HIV in San Francisco who died in 2002–2016

From: A longitudinal study assessing differences in causes of death among housed and homeless people diagnosed with HIV in San Francisco

Cause of Death among San Francisco Residents Cause of Death among Non-San Francisco Residents
Cause of Death N (%) Trend Test p value Cause of Death N (%) Trend Test p value
Accidental death (including drug related)   <.0001 Accidental death (including drug related)   0.6497
 2002–2004 24 (3.64)   2002–2004 27 (8.11)  
 2005–2007 61 (9.58)   2005–2007 37 (10.66)  
 2008–2010 65 (13.77)   2008–2010 29 (10.47)  
 2011–2013 58 (12.89)   2011–2013 27 (10.15)  
 2014–2016 60 (14.56)   2014–2016 29 (9.54)  
AIDS cancer   < 0.0001 AIDS cancer   0.1002
 2002–2004 72 (10.91)   2002–2004 33 (9.91)  
 2005–2007 60 (9.42)   2005–2007 19 (5.48)  
 2008–2010 33 (6.99)   2008–2010 29 (10.47)  
 2011–2013 28 (6.22)   2011–2013 20 (7.52)  
 2014–2016 19 (4.61)   2014–2016 15 (4.93)  
AIDS opportunistic infections (excluding AIDS cancers)   < 0.0001 AIDS opportunistic infections (excluding AIDS cancers)   0.0639
 2002–2004 188 (28.48)   2002–2004 81 (24.32)  
 2005–2007 153 (24.02)   2005–2007 79 (22.77)  
 2008–2010 98 (20.76)   2008–2010 56 (20.22)  
 2011–2013 79 (17.56)   2011–2013 47 (17.67)  
 2014–2016 73 (17.72)   2014–2016 61 (20.07)  
Alcohol related liver disease   0.1152 Alcohol related liver disease   0.4591
 2002–2004 7 (1.06)   2002–2004 5 (1.50)  
 2005–2007 6 (0.94)   2005–2007 3 (0.86)  
 2008–2010 6 (1.27)   2008–2010 2 (0.36)  
 2011–2013 6 (1.33)   2011–2013 0 (0.00)  
 2014–2016 9 (2.18)   2014–2016 4 (1.32)  
Assault   0.1028 Assault   0.0490
 2002–2004 3 (0.45)   2002–2004 1 (0.30)  
 2005–2007 5 (0.78)   2005–2007 2 (0.58)  
 2008–2010 3 (0.64)   2008–2010 0 (0.00)  
 2011–2013 6 (1.33)   2011–2013 2 (0.75)  
 2014–2016 5 (1.21)   2014–2016 5 (1.64)  
Cardiomyopathy   0.0080 Cardiomyopathy   0.4488
 2002–2004 13 (1.97)   2002–2004 7 (2.10)  
 2005–2007 7 (1.10)   2005–2007 9 (2.59)  
 2008–2010 11 (2.33)   2008–2010 7 (2.53)  
 2011–2013 10 (2.22)   2011–2013 4 (1.50)  
 2014–2016 18 (4.37)   2014–2016 5 (1.64)  
Cerebral vascular event   0.1230 Cerebral vascular event   0.1221
 2002–2004 19 (2.88)   2002–2004 10 (3.00)  
 2005–2007 16 (2.51)   2005–2007 11 (3.17)  
 2008–2010 22 (4.66)   2008–2010 7 (2.53)  
 2011–2013 13 (2.89)   2011–2013 6 (2.26)  
 2014–2016 19 (4.61)   2014–2016 18 (5.92)  
COPD   0.1489 COPD   0.0401
 2002–2004 37 (5.61)   2002–2004 17 (5.11)  
 2005–2007 48 (7.54)   2005–2007 7 (2.02)  
 2008–2010 39 (8.26)   2008–2010 12 (4.33)  
 2011–2013 28 (6.22)   2011–2013 17 (6.39)  
 2014–2016 36 (8.74)   2014–2016 21 (6.91)  
Diabetes   0.0804 Diabetes   0.0003
 2002–2004 14 (2.12)   2002–2004 4 (1.20)  
 2005–2007 29 (4.55)   2005–2007 11 (3.17)  
 2008–2010 18 (3.81)   2008–2010 11 (3.97)  
 2011–2013 25 (5.56)   2011–2013 22 (8.27)  
 2014–2016 15 (3.64)   2014–2016 16 (5.26)  
HIV/AIDS   < 0.0001 HIV/AIDS   < 0.0001
 2002–2004 557 (84.39)   2002–2004 259 (77.78)  
 2005–2007 472 (74.10)   2005–2007 243 (70.03)  
 2008–2010 314 (66.53)   2008–2010 194 (70.04)  
 2011–2013 284 (63.11)   2011–2013 164 (61.65)  
 2014–2016 258 (62.62)   2014–2016 183 (60.20)  
Heart disease   0.0004 Heart disease   < 0.0001
 2002–2004 132 (20.00)   2002–2004 73 (21.92)  
 2005–2007 128 (20.09)   2005–2007 79 (22.77)  
 2008–2010 132 (27.97)   2008–2010 79 (28.52)  
 2011–2013 99 (22.00)   2011–2013 89 (33.46)  
 2014–2016 121 (29.97)   2014–2016 101 (33.22)  
Ischemic   0.0408 Ischemic   0.0494
 2002–2004 37 (5.61)   2002–2004 25 (7.51)  
 2005–2007 36 (5.65)   2005–2007 23 (6.63)  
 2008–2010 36 (7.63)   2008–2010 28 (10.11)  
 2011–2013 35 (7.78)   2011–2013 24 (9.02)  
 2014–2016 33 (8.01)   2014–2016 34 (11.18)  
Liver disease   0.0539 Liver disease   0.2200
 2002–2004 111 (16.82)   2002–2004 52 (15.62)  
 2005–2007 85 (13.34)   2005–2007 41 (11.82)  
 2008–2010 67 (14.19)   2008–2010 37 (13.36)  
 2011–2013 56 (12.44)   2011–2013 30 (11.28)  
 2014–2016 53 (12.84)   2014–2016 37 (12.17)  
Mental disorders   0.2685 Mental disorders   0.0035
 2002–2004 61 (9.34)   2002–2004 25 (7.51)  
 2005–2007 74 (11.62)   2005–2007 36 (10.37)  
 2008–2010 50 (10.59)   2008–2010 28 (10.11)  
 2011–2013 43 (9.56)   2011–2013 36 (13.53)  
 2014–2016 31 (7.52)   2014–2016 43 (14.14)  
Mental disorders due to substance abuse   0.3142 Mental disorders due to substance abuse   0.0061
 2002–2004 57 (8.64)   2002–2004 22 (6.61)  
 2005–2007 66 (10.36)   2005–2007 33 (9.51)  
 2008–2010 43 (9.11)   2008–2010 21 (7.58)  
 2011–2013 42 (9.33)   2011–2013 33 (12.41)  
 2014–2016 28 (6.80)   2014–2016 38 (12.50)  
Non-AIDS cancer   < 0.0001 Non-AIDS cancer   0.0003
 2002–2004 79 (11.97)   2002–2004 31 (9.31)  
 2005–2007 102 (16.01)   2005–2007 47 (13.54)  
 2008–2010 77 (16.31)   2008–2010 43 (15.52)  
 2011–2013 88 (19.56)   2011–2013 49 (18.42)  
 2014–2016 83 (20.15)   2014–2016 56 (18.42)  
Overdose   < 0.0001 Overdose   0.3463
 2002–2004 18 (2.73)   2002–2004 18 (5.41)  
 2005–2007 47 (7.38)   2005–2007 19 (5.48)  
 2008–2010 56 (11.86)   2008–2010 21 (7.58)  
 2011–2013 51 (11.33)   2011–2013 23 (8.65)  
 2014–2016 50 (12.14)   2014–2016 18 (5.92)  
Pancreatitis/ cancer   0.2176 Pancreatitis/ cancer   0.5330
 2002–2004 9 (1.36)   2002–2004 2 (0.60)  
 2005–2007 2 (0.31)   2005–2007 1 (0.29)  
 2008–2010 2 (0.42)   2008–2010 3 (1.08)  
 2011–2013 2 (0.44)   2011–2013 0 (0.00)  
 2014–2016 3 (0.73)   2014–2016 1 (0.33)  
Pneumonia   0.0045 Pneumonia   0.0264
 2002–2004 96 (14.55)   2002–2004 49 (14.71)  
 2005–2007 81 (12.72)   2005–2007 39 (11.24)  
 2008–2010 61 (12.92)   2008–2010 39 (14.08)  
 2011–2013 48 (10.67)   2011–2013 19 (7.14)  
 2014–2016 37 (8.98)   2014–2016 31 (10.20)  
Renal   0.4942 Renal   0.4874
 2002–2004 84 (12.73)   2002–2004 25 (7.51)  
 2005–2007 65 (10.20)   2005–2007 40 (11.53)  
 2008–2010 48 (10.17)   2008–2010 29 (10.47)  
 2011–2013 46 (10.22)   2011–2013 22 (8.27)  
 2014–2016 48 (11.65)   2014–2016 33 (10.86)  
Septicemia   0.3818 Septicemia   0.6743
 2002–2004 81 (12.27)   2002–2004 32 (9.61)  
 2005–2007 66 (10.36)   2005–2007 34 (9.80)  
 2008–2010 45 (9.53)   2008–2010 28 (10.11)  
 2011–2013 47 (10.44)   2011–2013 22 (8.27)  
 2014–2016 44 (10.68)   2014–2016 28 (9.21)  
Suicide   0.8411 Suicide   0.2143
 2002–2004 16 (2.42)   2002–2004 9 (2.70)  
 2005–2007 24 (3.77)   2005–2007 12 (3.46)  
 2008–2010 22 (4.66)   2008–2010 10 (3.61)  
 2011–2013 14 (3.11)   2011–2013 12 (4.51)  
 2014–2016 11 (2.67)   2014–2016 13 (4.28)  
Viral hepatitis   0.0603 Viral hepatitis   0.5918
 2002–2004 108 (16.36)   2002–2004 50 (15.02)  
 2005–2007 97 (15.23)   2005–2007 39 (10.37)  
 2008–2010 58 (12.29)   2008–2010 32 (11.55)  
 2011–2013 59 (12.89)   2011–2013 31 (11.65)  
 2014–2016 55 (13.35)   2014–2016 39 (12.83)  
  1. P values < 0.05 are shown in bold
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