Table 2 Characteristics of the subgroups aged < or ≥ 50 years

 Control n (%)

15 (53.6)

14 (56)

1,00^a

 Intervention n (%)

13 (46.4)

11 (44)

 Female n (%)

6 (21.4)

13 (52)

0,0254^a

 Male n (%)

22 (78.6)

12 (48)

 Mean (SD)

37.71 (9.54)

56.36 (4.31)

P < 0.0001^b

 Median (25%; 75%)

39.0 (28.5; 45.75)

56.0 (53.0; 58.5)

 Mean (SD)

10.75 (20.06)

6.10 (14.26)

0,21^c

 Median (25%; 75%)

4.0 (2.0; 9.0)

2.0 (0.275; 5.0)

 Mean (SD)

5.89 (6.01)

6.92 (7.94)

0,73^c

 Median (25%; 75%)

4.0 (1.0; 9.0)

4.0 (2.0; 9.5)

 Mean (SD)

14.63 (9.68)

21.92 (14.7)

0,0383^b

 Median (25%; 75%)

14.0 (7.0; 20.0)

19.0 (10.5; 34.0)

 Mean (SD)

28.44 (6.34)

29.72 (6.26)

0,31^c

 Median (25%; 75%)

26.45 (24.3; 32.7)

29.0 (25.25; 32.1)

 Psoriatic arthritis, n (%)

6 (21.4)

12 (48)

0,0492^a

 Depression, n (%)

3 (11.1)

8 (32)

0,09^a

 Allergy, n (%)

7 (25.9)

10 (40)

0,38^a

 Hypertension, n (%)

7 (25.9)

12 (48)

0,15^a

 Cardiovascular diseases, n (%)

1 (3.7)

2 (8)

0,60^a

 Hypercholesterolemia, n (%)

4 (14.8)

7 (28)

0,32^a

 COPD, asthma, n (%)

2 (7.4)

7 (28)

0,07^a

 Hepatitis, cirrhosis of the liver, other liver diseases, n (%)

1 (3.7)

2 (8)

0,60^a

 Diabetes mellitus, n (%)

2 (7.4)

3 (12)

0,66^a

 Cancer, n (%)

0

1 (4)

0,48^a

 No comorbidities, n (%)

11 (40.7)

3 (12)

0,0287^a

 Current smoker, n (%)

9 (32.1)

11 (47.8)

0,39^a

 Ex-smoker, n (%)

8 (28.6)

8 (34.8)

0,76^a

 Non-smoker, n (%)

11 (39.3)

4 (17.4)

0,13^a