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Table 1 Baseline characteristics of the study population by haemoglobin trajectory groups

From: Trajectories of Haemoglobin and incident stroke risk: a longitudinal cohort study

Variables

Haemoglobin trajectory classes

High-stable

(N = 5395)

Normal-stable

(N = 5310)

Decreasing

(N = 726)

p-value

Age at entry, year

34.4 (7.2) *

33.7 (7.1)

33.8 (6.6)

< 0.001

Men, n (%)

3146 (58.3) *

3234 (60.9)

169 (23.3) *

< 0.001

BMI, kg/m2

24.1 (3.6) *

23.5 (3.6)

22.6 (3.2) *

< 0.001

Hypertension, n (%)

1473 (27.3) *

1050 (19.8)

109 (15.0) *

< 0.001

Dyslipidemia, n (%)

1983 (49.0) *

1604 (42.1)

189 (39.6)

< 0.001

Diabetes mellitus, n (%)

153 (2.8) *

100 (1.9)

20 (2.8)

0.004

GFR, mL/min per 1.73 m2

95.8 (14.4) *

98.0 (14.5)

96.2 (15.2)

< 0.001

Smoker, n (%)

835 (15.5) *

688 (13.0)

38 (5.2) *

< 0.001

Drinker, n (%)

1065 (19.7)

966 (18.2)

53 (7.3) *

< 0.001

Haemoglobin, g/L

 Baseline level

149.3 (13.0) *

138.8 (13.0)

119.3 (24.7) *

< 0.001

 Mean level

149.0 (12.2) *

138.1 (12.2)

117.0 (21.2) *

< 0.001

 Minimum level

143.5 (12.9) *

132.2 (13.4)

103.3 (21.9) *

< 0.001

 Maximum level

154.4 (12.5) *

143.7 (12.2)

130.0 (22.4) *

< 0.001

Age at stroke, year

46.0 (5.6)

45.3 (5.9)

45.0 (5.3)

0.707

Median follow-up years

4.5 (1.1–12.4)

4.4 (1.1–12.7)

4.8 (1.7–11)

0.208

Stroke incidence density, per 1000 person-years

2.7 *

1.9

3.2

0.046

  1. Data are presented as mean (SD), median (range) or percentage. P values were calculated from the comparison between 3 identified trajectory classes
  2. * Compared with the Normal-stable class: P < 0.05
  3. Abbreviations: BMI body mass index, GFR glomerular filtration rate