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Table 4 Adjusted generalized estimating equations of the effect of different interventions in lipid profile and blood pressure

From: Supervised training in primary care units but not self-directed physical activity lowered cardiovascular risk in Brazilian low-income patients: a controlled trial

VariableFA (n = 81)DA (n = 34)PI (n = 48)p-valuePower (1-β)
BaselineFollow-upBaselineFollow-upBaselineFollow-upInteraction 
Total cholesterol, mg/dL202.3 (192.9 to 212.2)187.3*a (178.1 to 197.0)200.7 (189.4 to 212.8)193.0 (180.3 to 206.6)183.1 (168.7 to 198.7)206.6* (188.9 to 225.8)0.0020.91
HDL-C, mg/dL49.7 (47.1 to 52.5)50.4 (47.8 to 53.1)50.2 (46.7 to 53.9)49.5 (45.8 to 53.6)47.3 (43.5 to 51.4)45.5 (41.9 to 49.5)0.5370.21
LDL-C, mg/dL124.9 (116.9 to 133.4)111.1*a (103.8 to 118.9)124.3 (114.1 to 135.3)113.2* (101.6 to 126.2)112.3 (101.0 to 124.9)128.8* (115.6 to 143.6)0.0010.86
Triglycerides, mg/dL145.6 (130.0 to 154.3)124.8*a (114.6 to 135.9)133.3 (116.9 to 152.0)141.0 (121.8 to 163.1)131.5 (115.7 to 149.4)158.2* (137.2 to 182.2)0.0010.99
PAS, mmHg131.9 (128.5 to 135.3)114.0*ab (111.2 to 116.8)135.6 (131.1 to 140.3)134.4 (129.4 to 139.5)132.2 (127.5 to 137.1)141.4* (136.0 to 147.0)< 0.0011.00
PAD, mmHg82.9 (80.8 to 84.9)77.7*ab (76.3 to 79.2)84.6 (82.6 to 86.6)82.8 (79.5 to 86.3)84.8 (82.8 to 87.0)86.2 (83.6 to 88.9)< 0.0010.83
  1. FA formally active group, DA declared active group, PI physically inactive group. BMI body mass index, HDL-C high density lipoprotein – cholesterol, LDL-C low density lipoprotein – cholesterol, SBP systolic blood pressure, DBP diastolic blood pressure. Note: Intention-to-treat: FA includes individuals that completed the supervised training (n = 53) and dropouts (n = 28). Interaction refers to the interaction group vs. time. Analyses adjusted for sex, chronological age, body mass index and hypertensive/statin drugs ingestion. Values presented through estimated marginal means (95% confidence interval).
  2. (Bold data) *P < 0.05 vs. Baseline, aP < 0.05 vs. PI, bP < 0.05 vs. DA