Table 2 Risk Factors for isoniazid treatment interruptions among latent tuberculosis cases followed for 12 months
Predictors | Unadjusted HR (95% CI) | Adjusted HR (95% CI) |
|---|---|---|
Type of Patient | ||
 Pediatric | 0.87 (0.82, 0.93) | 0.83 (0.78, 0.89) |
 Recent Contact | 0.74 (0.69, 0.81) | 0.74 (0.68, 0.81) |
 Other Adults | 1.00 | 1.00 |
Gender | ||
 Male | 1.00 | 1.00 |
 Female | 0.91 (0.86, 0.95) | 0.90 (0.85, 0.94) |
Ethnicity | ||
 Non-Hispanic | 1.00 | 1.00 |
 Hispanic | 1.46 (1.38, 1.53) | 1.54 (1.43, 1.66) |
Race | ||
 White | 1.28 (1.19, 1.37) | 1.26 (1.18, 1.36) |
 Black | 1.14 (1.06, 1.22) | 1.57 (1.44, 1.70) |
 Asian | 0.58 (0.51, 0.66) | 0.77 (0.67, 0.89) |
 Other | 1.00 | 1.00 |
Birth Origin | ||
 U.S.-born | 1.00 | 1.00 |
 Non-U.S.-born, ≤ 5 Years | 1.34 (1.27, 1.41) | 1.25 (1.18, 1.32) |
 Non-U.S.-born, >  5 Years | 1.24 (1.12, 1.37) | 1.16 (1.04, 1.29) |
HIV Co-infected | ||
 No | 1.00 | 1.00 |
 Yes | 0.41 (0.31, 0.53) | 0.39 (0.30, 0.51) |
Diabetic | ||
 No | 1.00 | 1.00 |
 Yes | 0.73 (0.57, 0.94) | 0.77 (0.60, 0.98) |
Other Immunosuppressive Conditions | ||
 No | 1.00 | 1.00 |
 Yes | 0.59 (0.42, 0.85) | 0.65 (0.46, 0.93) |