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Table 5 Incremental cost-effectiveness of 10- valent pneumococcal conjugate vaccine in terms of averted DALYs during three years follow-up from inclusion in the study in the intervention group, vaccinated sub-group (Sep. 2011 – Aug. 2012) and control group (Sep. 2009 – Aug. 2010) at Butajira rural health program site

From: Cost-effectiveness of childhood pneumococcal vaccination program in Ethiopia: results from a quasi-experimental evaluation

Health outcomes

Cost*

Incremental cost

Effectiveness

Incremental effectiveness

Incremental cost- effectiveness ratio (ICER)

 

No discounting

Discounting 3%

DALYs

 < 1 year of age

  Intervention

36.7

30.2

0.08

−0.01

Dominated

Dominated

  Vaccinated

36.2

29.7

0.11

−0.04

Dominated

Dominated

  Control

6.5

 

0.07

   

 > 1 year of age

  Intervention

36.3

30.0

0.0001

0.14

219.4

227.9

  Vaccinated

32.9

26.6

0.0001

0.13

194.2

273.9

  Control

6.3

 

0.1338

   

 > 2 years of age

  Intervention

31.0

29.2

0.00005

0.103

283.7

318.6

  Vaccinated

29.1

27.2

0.00003

0.1009

264.9

282.6

  Control

1.86

 

0.103

   

 Total follow-up period

  Intervention

46.1

33.3

0.08

0.12

268.0

281.4

  Vaccinated

42.2

29.3

0.11

0.10

304.7

342.0

  Control

12.8

 

0.20

   
  1. * N.B: the costs for averted DALYs and ALRI incidences are not the same due to the difference in considered costs. For DALYs, all costs in relation to all infections and vaccination were considered. In the case of ALRI, only costs related to ALRI and vaccination were considered