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Table 3 Association between depression status, anxious distress, and type 2 diabetes, stratified by age at enrolment

From: Severity of depression, anxious distress and the risk of type 2 diabetes – a population-based cohort study in Sweden

  Model 1 Model 2 Model 3 Model 4
OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Age < 50 years
 Depression status
  No 1 1 1 1
  Yes 1.71 (1.16–2.51) 1.90 (1.29–2.80) 1.70 (1.14–2.55) 1.56 (1.03–2.38)
Level of depression
 No depression 1 1 1 1
 Mild depression 1.44 (0.77–2.70) 1.61 (0.86–3.02) 1.49 (0.79–2.81) 1.57 (0.81–3.02)
 Moderate depression 1.41 (0.65–3.06) 1.55 (0.71–3.38) 1.42 (0.65–3.11) 1.31 (0.58–2.95)
 Severe depression 2.14 (1.28–3.60) 2.41 (1.43–4.07) 2.09 (1.21–3.60) 1.70 (0.96–3.00)
Depression with/without levels anxious distress
 No depression or anxious distress 1 1 1 1
 Depression without anxious distress 1.69 (0.85–3.38) 1.92 (0.96–3.84) 1.79 (0.89–3.61) 1.57 (0.76–3.24)
 Depression with mild anxious distress 1.51 (0.81–2.83) 1.64 (0.87–3.07) 1.48 (0.78–2.80) 1.40 (0.72–2.72)
 Depression with moderate/severe anxious distress 1.89 (1.09–3.27) 2.14 (1.23–3.73) 1.86 (1.05–3.28) 1.71 (0.94–3.10)
Age ≥ 50 years
Depression status
 No 1 1 1 1
 Yes 1.05 (0.69–1.61) 1.18 (0.77–1.82) 1.04 (0.67–1.61) 0.97 (0.61–1.53)
Level of depression
 No depression 1 1 1 1
 Mild depression 1.27 (0.67–2.40) 1.47 (0.77–2.80) 1.32 (0.69–2.52) 1.25 (0.63–2.46)
 Moderate depression 0.47 (0.15–1.50) 0.52 (0.16–1.68) 0.48 (0.15–1.55) 0.45 (0.14–1.46)
 Severe depression 1.24 (0.67–2.28) 1.37 (0.74–2.52) 1.15 (0.62–2.15) 1.07 (0.56–2.06)
Depression with/without levels anxious distress
 No depression or anxious distress 1 1 1 1
 Depression without anxious distress 0.93 (0.43–2.03) 1.11 (0.51–2.44) 1.01 (0.46–2.24) 0.91 (0.40–2.06)
 Depression with mild anxious distress 0.82 (0.38–1.78) 0.89 (0.41–1.94) 0.80 (0.36–1.75) 0.72 (0.32–1.63)
 Depression with moderate/severe anxious distress 1.39 (0.75–2.56) 1.54 (0.83–2.85) 1.29 (0.69–2.42) 1.26 (0.66–2.44)
  1. Logistic regression analyses with type 2 diabetes (T2DM) as the outcome variable. CI,Confidence Interval, OR Odds Ratio, MDI Major Depression Inventory
  2. Model 1 Crude
  3. Model 2 Adjusted for sex
  4. Model 3 Adjusted for sex and socioeconomic position
  5. Model 4 Adjusted for sex, socioeconomic position, smoking, alcohol use, physical activity, body mass index