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Table 5 Cox proportional hazards analysis of cancer-specific death and all-causes death for subgroups of CRC patients

From: The impact of screening on the survival of colorectal cancer in Shanghai, China: a population based study

 Cancer-specific deathAll-causes death
HR(95% CI)P valueHR(95% CI)P value
Panel A: For CRC patients diagnosed after the introduction of the screening program
Program participation (Ref. group: Participants of the program)
 Non-participants of the program1.46(1.12–1.91)0.0061.37(1.05–1.77)0.019
Gender (Ref. group: Female)      
 Male1.24(1.06–1.45)0.0081.23(1.05–1.44)0.01
Age at diagnosis (Ref. group: ≤65 yrs)
  > 65 yrs1.49(1.28–1.74)< 0.0011.49(1.28–1.73)< 0.001
Sub-region (Ref. group: Rural)
 Urban0.96(0.82–1.12)0.5890.95(0.81–1.10)0.475
Level of treatment hospital (Ref. group: Tertiary)
 Secondary1.5(1.12–1.91)< 0.0011.49(1.28–1.73)< 0.001
TNM Stage (Ref. group: I + II)
 III + IV1.75(1.58–1.94)< 0.0011.77(1.60–1.95)< 0.001
Panel B: For CRC patients who participated in the screening program
Screening policy compliance (Ref. group: Compliant to the screening policy)
 Incompliant to the screening policy2.93(1.64–5.23)< 0.0013.29(1.85–5.84)< 0.001
Gender (Ref. group: Female)
 Male1.91(1.13–3.22)0.0151.73(1.06–2.84)0.029
Age at diagnosis (Ref. group: ≤65 yrs)
  > 65 yrs1.11(0.67–1.85)0.6741.18(0.72–1.93)0.506
Sub-region (Ref. group: Rural)
 Urban0.91(0.53–1.56)0.7180.86(0.51–1.46)0.579
Level of treatment hospital (Ref. group: Tertiary)
 Secondary1.31(0.80–2.14)0.2831.34(0.84–2.15)0.224
TNM Stage (Ref. group: I + II)
 III + IV8.55(4.54–16.13)< 0.0017.55(4.17–13.55)< 0.001
  1. Notes: Colorectal cancer, CRC; Hazard ratio, HR.