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Table 5 Cox proportional hazards analysis of cancer-specific death and all-causes death for subgroups of CRC patients

From: The impact of screening on the survival of colorectal cancer in Shanghai, China: a population based study

 

Cancer-specific death

All-causes death

HR

(95% CI)

P value

HR

(95% CI)

P value

Panel A: For CRC patients diagnosed after the introduction of the screening program

Program participation (Ref. group: Participants of the program)

 Non-participants of the program

1.46

(1.12–1.91)

0.006

1.37

(1.05–1.77)

0.019

Gender (Ref. group: Female)

      

 Male

1.24

(1.06–1.45)

0.008

1.23

(1.05–1.44)

0.01

Age at diagnosis (Ref. group: ≤65 yrs)

  > 65 yrs

1.49

(1.28–1.74)

< 0.001

1.49

(1.28–1.73)

< 0.001

Sub-region (Ref. group: Rural)

 Urban

0.96

(0.82–1.12)

0.589

0.95

(0.81–1.10)

0.475

Level of treatment hospital (Ref. group: Tertiary)

 Secondary

1.5

(1.12–1.91)

< 0.001

1.49

(1.28–1.73)

< 0.001

TNM Stage (Ref. group: I + II)

 III + IV

1.75

(1.58–1.94)

< 0.001

1.77

(1.60–1.95)

< 0.001

Panel B: For CRC patients who participated in the screening program

Screening policy compliance (Ref. group: Compliant to the screening policy)

 Incompliant to the screening policy

2.93

(1.64–5.23)

< 0.001

3.29

(1.85–5.84)

< 0.001

Gender (Ref. group: Female)

 Male

1.91

(1.13–3.22)

0.015

1.73

(1.06–2.84)

0.029

Age at diagnosis (Ref. group: ≤65 yrs)

  > 65 yrs

1.11

(0.67–1.85)

0.674

1.18

(0.72–1.93)

0.506

Sub-region (Ref. group: Rural)

 Urban

0.91

(0.53–1.56)

0.718

0.86

(0.51–1.46)

0.579

Level of treatment hospital (Ref. group: Tertiary)

 Secondary

1.31

(0.80–2.14)

0.283

1.34

(0.84–2.15)

0.224

TNM Stage (Ref. group: I + II)

 III + IV

8.55

(4.54–16.13)

< 0.001

7.55

(4.17–13.55)

< 0.001

  1. Notes: Colorectal cancer, CRC; Hazard ratio, HR.