Trajectories of seasonal influenza vaccine uptake among French people with diabetes: a nationwide retrospective cohort study, 2006–2015

Table 1 Study cohort characteristics during the first and last seasons n/n + 1 of follow-up (EGB, France, 2006/07–2015/16)

	2006/07 (n = 17,259)	2015/16 (n = 11,440)^a
	%^b	%^b
Sociodemographic characteristics
Age (years) on 12.31.n – mean (SD)	65.0 (13.7)	70.5 (12.8)
Women	46.1	47.1
Clinical characteristics
Type and treatment of diabetes
Type 1 diabetes^c	9.2	11.2
Other types -- no antidiabetic drug	15.8	9.2
Other types - only one noninsulin antidiabetic drug	35.3	22.0
Other types -- ≥ 2 noninsulin antidiabetic drugs	28.2	33.6
Other types -- insulin treatment ± antidiabetic drugs	11.5	24.0
Weighted individual chronic condition score^d – mean (SD)	0.8 (0.5)	0.9 (0.5)
Annual rate of hospitalization for diabetes or its complications^e	6.2	4.3
Annual rate of hospitalization for influenza or its complications^e	0.7	1.4
Healthcare utilization
Annual number of consultations^f with -- mean (SD)
General practitioner	8.6 (7.3)	7.9 (6.4)
Endocrinologist	0.3 (1.2)	0.4 (1.2)
Cardiologist	0.5 (1.5)	0.5 (1.4)
Change of general practitioner	4.0	10.3
Received free vaccination voucher for diabetes^g	69.9	90.3

SD standard deviation
^aAmong all patients included in the cohort, 5266 (30.5%) died and 553 (3.2%) were lost during follow-up. Mean follow-up time: 8.24 ± 2.90 seasons
^bOtherwise stated
^cPeople with type 1 diabetes were those with long-term illness status for type 1 diabetes (E10 according to the ICD-10) and treated by insulin at inclusion
^dThe individual chronic condition score (ICC) was calculated as a weighted sum of 21 chronic conditions. Weights account for the severity of each condition in the score calculation (ICC range in study cohort: min = 0; max = 3.7)
^eAt least 1 hospitalization between 09.01.n-1 and 08.31.n
^fNumber of consultations between 09.01.n-1 and 08.31.n
^gTo identify people with diabetes, the National Health Insurance Fund uses only their Long-Term Illness (LTI) status on September 1 of each year. Nonetheless, not all patients with diabetes (especially those with diabetes other than type 1) receive the voucher, because some who should have LTI status do not apply for it

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