Soya, maize and sorghum ready-to-use therapeutic foods are more effective in correcting anaemia and iron deficiency than the standard ready-to-use therapeutic food: randomized controlled trial

Table 4 Adjusted prevalence of anaemia, ID and IDA at discharge across study arms^a

	n	%(95%CI)^f	Unadjusted difference		Adjusted difference^b		p-value^e
	n	%(95%CI)^f	Diff^g	(95%CI)	Diff	(95%CI)	p-value^e
Prevalence of anaemia^c at discharge
All children
FSMS-RUTF	83	12.0 (6.9–20.3)	Base		Base
MSMS-RUTF	77	18.2 (11.9–26.8)	6.1	(−0.6; 18.3)	7.6	(−3.9; 19.0)	0.195
PM-RUTF	106	24.5 (15.8–35.9)	12.5	(1.2; 23.7)	12.6	(2.1; 23.1)	0.019
Without anaemia at admission
FSMS-RUTF	43	4.6 (1.0–19.2)	Base		Base
MSMS-RUTF	35	5.7 (0.8–31.5)	1.1	(−9.1; 11.2)	5.7	(−5.2; 16.6)	0.303
PM-RUTF	59	11.9 (5.5–23.7)	7.2	(−3.6; 18.0)	7.1	(−2.4, 16.5)
With anaemia at admission
FSMS-RUTF	38	18.4 (10.0–31.3)	Base		Base
MSMS-RUTF	40	30.0 (20.0–42.3)	11.6	(−8.8; 32.0)	12.8	(−0.3; 35.0)	0.254
PM-RUTF	45	40.0 (26.0–55.9)	21.6	(1.7; 41.4)	22.2	(2.9; 41.5)	0.024
Prevalence of iron deficiency^d at discharge
All children
FSMS-RUTF	64	42.2 (29.1–56,4)	Base		Base
MSMS-RUTF	46	60.9 (49.4–71.2)	18.7	(−0.1; 37.5)	25.3	(6.6; 44.0)	0.008
PM-RUTF	84	58.3 (44.9–70.7)	16.1	(−0.1; 34.2)	20.6	(4.8;36.4)	0.011
Iron deficient at admission
FSMS-RUTF	36	47.2 (29.5–65.7)	Base		Base
MSMS-RUTF	21	85.7 (56.1–96.6)	38.5	(15.5; 61.2)	38.7	(17.7; 59.6)	< 0.001
PM-RUTF	43	83.7 (73.9–90.3)	36.5	(16.2; 56.7)	35.0	(14.7; 55.2)	0.001
Prevalence of iron deficiency anaemia at discharge
All children
FSMS-RUTF	63	7.9 (3.4–17.3)	Base		Base
MSMS-RUTF	46	10.9 (4.8–22.6)	2.9	(−8.4; 14.3)	2.9	(−8.5; 14.4)	0.611
PM-RUTF	83	20.5 (10.7–35.5)	12.5	(1.4; 23.6)	10;8	(0.6; 21.1)	0.039

^aStudy arms: FSMS-RUTF Milk Free Soya-Maize-Sorghum Based Ready-To-Use Therapeutic Food, MSMS-RUTF Milk Soya-Maize-Sorghum Based Ready-To-Use Therapeutic Food and PM-RUTF Peanut milk based Ready-To-Use Therapeutic Food
^badjusted for age, gender, mother level of education, anaemia at admission and presence of iron deficiency using the body iron store based criterion
^cAnaemia diagnosed based on altitude- and ethnicity-corrected haemoglobin
^dIron status according to inflammation-corrected soluble transferrin receptor values
^ep-value for the adjusted difference obtained by multivariable linear regression
^fCI confidence interval
^gDiff difference

ISSN: 1471-2458