Table 2 The APEASE criteria for designing and evaluating interventions

Affordability

The ability of the intervention to meet the expense of the intervention. An intervention is affordable if the budget of the intervention allows it to be delivered to, or accessed by, all those for whom it is intended.

Practicability

The viability of the intervention. A practicable intervention is one that can be delivered as designed through the means intended to the target population.

Effectiveness and cost-effectiveness

The effect size of the intervention in relation to the desired objectives in a real world context. Cost-effectiveness refers to the ratio of effect to cost.

Acceptability

The extent to which relevant stakeholders (public, professional and political) judge an intervention appropriate.

Side-effects/Safety

An intervention may be effective and practicable but have unwanted or unintended consequences. This needs to be taken into consideration when planning the intervention.

Equity

The extent to which an intervention may reduce or increase the disparities in standard of living, wellbeing or health between different sectors of society.