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Table 2 Hazard ratios (95%CI) for risk of type 2 diabetes according to waist circumference group by trajectory analysis, N = 4, 992

From: Waist circumference trajectories and risk of type 2 diabetes mellitus in Korean population: the Korean genome and epidemiology study (KoGES)

 

No. of Persons

No. of T2DM incidences

Person years, follow-up

Age adjusted rate

Model 1a

Model 2b

Model 3c

HR (95% CI)

HR (95% CI)

HR (95% CI)

WC Group A

635

9

4033.6

193.9

1.0

1.0

1.0

WC Group B

1426

52

8984.2

498.4

2.6 (1.3–5.2)

2.5 (1.2–5.0)

2.2 (1.1–4.6)

WC Group C

1662

75

10,392.1

661.9

3.2 (1.6–6.4)

3.0 (1.5–5.9)

2.5 (1.2–5.0)

WC Group D

1012

104

6158.6

1845.9

7.4 (3.7–14.8)

7.0 (3.5–13.8)

5.4 (2.7–10.9)

WC Group E

257

36

1549.2

2045.0

10.0 (4.8–20.7)

10.0 (4.8–20.8)

7.3 (3.5–15.4)

P for trend

    

<.0001

<.0001

<.0001

C statistic

    

0.6841

0.6956

0.8689

  1. Abbreviation: T2DM type 2 diabetes mellitus, WC waist circumference, HR hazard ratio, CI confidence interval
  2. aModel 1: Adjusted for age, age square, sex, and family history of type 2 diabetes mellitus at wave 4
  3. bModel 2: Adjusted for Model 2 + smoking status, alcohol intake, physical exercise, and body mass index at wave 4
  4. cModel 3: Adjusted for Model 3 + systolic blood pressure, and total cholesterol at wave 4