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Table 5 Hazard Ratios and population attributable fraction from the multi-variable analysis of potential risk factors in relation to premature mortality excluded current smokers, prevalent CVD/cancer and survival less than 3 years; Tehran Lipid and Glucose study (1999–2014)

From: Incidence and associated risk factors for premature death in the Tehran Lipid and Glucose Study cohort, Iran

 

Hazard ratio (95% CI)

P value

Prevalencea

PAF, %b

Sex (Female)

0.67 (0.46–0.97)

0.036

0.55 (0.47–0.63)

−27.1

Body mass index

 Normal

Reference

 

0.30 (0.23–0.38)

 

 Overweight

0.59 (0.39–0.88)

0.011

0.36 (0.29–0.44)

−25.0

 Obese

0.67 (0.43–1.04)

0.072

0.33 (0.26–0.41)

−16.3

Hypercholesterolemia,

1.05 (0.74–1.50)

0.781

0.38 (0.30–0.46)

 

Hypertension

1.12 (0.78–1.60)

0.536

0.40 (0.31–0.47)

 

Diabetes

2.62 (1.84–3.72)

< 0.001

0.37 (0.30–0.45)

22.9

Education

 Primary/Illiterate

Reference

 

0.58 (0.50–0.66)

 

 Cycle/Diploma

0.98 (0.66–1.46)

0.923

0.32 (0.24–0.39)

 

 Higher than diploma

1.17 (0.64–2.11)

0.611

0.10 (0.05–0.15)

 

Low physical activity

1.35 (0.91–2.00)

0.139

0.23 (0.17–0.30)

 

FH-CVD

1.58 (1.07–2.32)

0.022

0.23 (0.16–0.30)

8.4

  1. All definitions and variables explained as footnotes for Table 2
  2. aPrevalence and CI of the risk factors among individuals who had an event
  3. bPAF: population attributable fraction calculated for p value< 0.05; formula for calculating PAF=P×[(HRadj 1)/HRadj] × 100
  4. CI confidence interval, CVD cardiovascular disease, P prevalence