Protocol of a two arm randomised, multi-centre, 12-month controlled trial: evaluating the impact of a Cognitive Behavioural Therapy (CBT)-based intervention Supporting UPtake and Adherence to antiretrovirals (SUPA) in adults with HIV

Table 1 Sample size calculations for Phase 2 – trial

Standard of care group % with > 0.8 of follow-up months with ≥90% adherence	Intervention group % with > 0.8 of follow-up months with ≥90% adherence	N per arm	Total N
35%	50%	183	366
45%	60%	186	372
50%	65%	183	366
60%	75%	165	330
70%	85%	134	268

ISSN: 1471-2458

Standard of care group % with > 0.8 of follow-up months with ≥90% adherence	Intervention group % with > 0.8 of follow-up months with ≥90% adherence	N per arm	Total N
35%	50%	183	366
45%	60%	186	372
50%	65%	183	366
60%	75%	165	330
70%	85%	134	268

Standard of care group % with > 0.8 of follow-up months with ≥90% adherence	Intervention group % with > 0.8 of follow-up months with ≥90% adherence	N per arm	Total N
35%	50%	183	366
45%	60%	186	372
50%	65%	183	366
60%	75%	165	330
70%	85%	134	268

Standard of care group % with > 0.8 of follow-up months with ≥90% adherence	Intervention group % with > 0.8 of follow-up months with ≥90% adherence	N per arm	Total N
35%	50%	183	366
45%	60%	186	372
50%	65%	183	366
60%	75%	165	330
70%	85%	134	268