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Table 4 Choices of treatment and comorbidity for IBD patients from 1980 until 2018

From: A four-decade analysis of the incidence trends, sociodemographic and clinical characteristics of inflammatory bowel disease patients at single tertiary centre, Kuala Lumpur, Malaysia

Characteristics

Ulcerative Colitis

N = 281

Crohn’s Disease

N = 132

Treatment, n (%)

 5-ASA

264 (94)

40 (30)

 Immunomodulator

74 (26)

82 (62)

  Azathioprine

73

80

  Mercaptopurine (6-MP)

1

2

 Steroid

7 (4.7)

8 (11.4)

 Biologics

10 (3.6)

36 (27.3)

  Adalimumab

0

16

  Infliximab

9

16

  Golimumab

1

0

  Ustekinumab

0

1

  Vedolizumab

0

3

 Curcumin extract

0

1

 No treatment

9 (3.2)

4 (3.0)

Surgery, n (%)

11 (3.9%)

46 (34.8)

 Panproctocolectomy + ileostomy

10

N/A

 Ileorectal anastomotic resection + ileostomy

1

N/A

 Right hemicolectomy

N/A

10

 Total colectomy

N/A

3

 Right limited hemicolectomy

NA

4

 Right transverse colostomy

N/A

2

 Segmental colectomy

N/A

1

 Small bowel resection

N/A

8

 Incision and drainage for fistula

N/A

8

 Seton insertion for fistula

N/A

13

Major Comorbidity, n (%)

 Type 2 Diabetes Mellitus

50 (17.8)

6 (4.5)

 Hypertension

39 (13.9)

12 (9.1)

 Dyslipidemia

32 (11.4)

2 (1.5)

 Ischemic Heart Disease

8 (2.8)

1 (0.7)

 Asthma

7 (2.5)

2 (1.5)

 Chronic kidney disease

2 (0.7)

1 (0.7)