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Table 1 Demographic and clinical characteristics of children empirically treated for TB at Mulago Pediatric TB unit (N = 516)*

From: Outcomes of empiric treatment for pediatric tuberculosis, Kampala, Uganda, 2010–2015

Characteristic Favorable (N = 422) Unfavorable (N = 94) p-value
N (%, 95 CI) N (%, 95 CI)
Age group
  < 5 years 280 (66, 62–71) 57 (61,50–70) 0.006
 5–9 years 104 (25, 21–29) 18 (19, 12–28)
 10–14 years 38 (9, 7–12) 19 (20, 13–30)
Male Sex 238 (56, 52–61) 48 (51, 41–61) 0.35
Reside outside of Kampala 174 (41, 37–46) 62 (66, 56–75) < 0.001
Pulmonary TB (n = 515) 291 (69, 65–73) 53 (67, 57–76) 0.69
HIV positive (n = 509) 19 (5, 3–7) 12 (14, 8–23) 0.001
Severe Malnutrition (n = 349) 60 (20, 16–25) 16 (32, 20–46) 0.06
Hospitalized (n = 480) 33 (8, 6–11) 26 (34, 24–45) < 0.001
Abnormal Chest X-ray (n = 367) 297 (93, 90–96) 46 (94, 82–98) 1.0
BCG vaccinated (n = 301) 239 (92, 88–95) 35 (83, 68–92) 0.06
Baseline Hepatomegaly (n = 383) 28 (8, 6–12) 13 (30, 18–46) < 0.001
TST Positive (n = 246) 161 (75, 69–80) 18 (58, 40–74) 0.05
  1. *N = 516 unless missing data, with number available indicated in parentheses
  2. p-value by Chi-squared or Fisher’s exact testing
  3. ‡ Severe malnutrition defined as weight-for-age Z score less than − 3