Table 3 Cox multivariate-adjusted HRs for all-cause mortality in the EPIC-Norfolk 1993-2015 per 70cL/s increase in FEV1 in subgroups adjusted by age and other covariates

All

4734/19139

0.71(0.68, 0.73)

<0.001

0.74(0.71, 0.77)

<0.001

 Men

2572/8719

0.72(0.69, 0.76)

<0.001

0.77(0.73, 0.81)

<0.001

 Women

2162/8258

0.67(0.62, 0.72)

<0.001

0.68(0.63, 0.74)

<0.001

 <65

1661/13631

0.74(0.70, 0.78)

<0.001

0.79(0.74, 0.84)

<0.001

 ≥65

3073/5508

0.67(0.65, 0.71)

<0.001

0.70(0.67, 0.74)

<0.001

Excluding early deaths < 5 years

4196/18601

0.72(0.69, 0.75)

<0.001

0.76(0.72, 0.79)

<0.001

 -Current smokers

670/ 2214

0.72(0.65, 0.80)

<0.001

0.71(0.63, 0.79)

<0.001

 -Ex-smokers

2344/7955

0.71(0.67, 0.75)

<0.001

0.72(0.68, 0.76)

<0.001

 -Never smokers

1720/8970

0.81(0.75, 0.87)

<0.001

0.82(0.76, 0.89)

<0.001

 <27 kg/m²

2759/12146

0.69(0.66, 0.73)

<0.001

0.73(0.69, 0.77)

<0.001

 ≥27 kg/m²

1975/6993

0.72(0.69, 0.78)

<0.001

0.75(0.71, 0.81)

<0.001

By physical activity

 - Inactive

1977/5467

0.65(0.62, 0.69)

<0.001

0.68(0.64, 0.72)

<0.001

 - Active

2757/13672

0.76(0.72, 0.80)

<0.001

0.79(0.75, 0.84)

<0.001

Excluding asthma or bronchitis

4772/17837

0.72(0.69, 0.75)

<0.001

0.76(0.73, 0.79)

<0.001

 -Nonmanual social class

2737/11509

0.73(0.69, 0.77)

<0.001

0.75(0.71, 0.80)

<0.001

 -Manual social class

1997/7630

0.69(0.65, 0.73)

<0.001

0.72(0.68, 0.77)

<0.001

 -Less than median

2646/9206

0.71(0.67, 0.75)

<0.001

0.73(0.69, 0.77)

<0.001

 -more than median

2088/9933

0.74(0.69, 0.78)

<0.001

0.75(0.71, 0.80)

<0.001