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Table 3 Antimicrobial resistance by Shigella serotypes in Guatemala, 2007–2012

From: Burden of laboratory-confirmed shigellosis infections in Guatemala 2007-2012: results from a population-based surveillance system

Antimicrobial class Antimicrobial All Cases
N (%)a
N = 254
S. soneii
N (%)a
N = 88
S. flexneri
N (%)a
N = 152
S. boydii
N (%)a
N = 12
S. dysenteriae
N (%)a
N = 2
Aminoglycoside Gentamicin 3 (1.0) 1 (1.0) 1 (1.0) 1 (8.0) 0 (0.0)
Kanamycin 4 (2.0) 2 (3.0) 2 (2.0) 0 (0.0) 0 (0.0)
Streptomycin 212 (85.0) 87 (99.0) 112 (76.0) 11 (92.0) 2 (100.0)
Beta-lactams Ampicillin 141 (61.0) 45 (58.0) 87 (61.0) 8 (67.0) 1 (50.0)
Amoxicillin 117 (47.0) 36 (41.0) 72 (49.0) 8 (67.0) 1 (50.0)
Ceftriaxone 3 (2.0) 1 (2.0) 1 (1.0) 0 (0.0) 1 (50.0)
Quinolones Ciprofloxacin 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Nalidixic acid 1 (0.4) 0 (0.0) 1 (1.0) 0 (0.0) 0 (0.0)
Phenicol Chloramphenicol 37 (15.0) 2 (2.0) 35 (23.0) 0 (0.0) 0 (0.0)
Sulfonamide Trimethoprim sulfamethoxazole 210 (83.0) 82 (93.0) 118 (78.0) 9 (75.0) 1 (50.0)
Tetracycline Tetracycline 238 (96.0) 83 (94.0) 143 (97.0) 10 (91.0) 2 (100.0)
Level of resistance   All Cases
N (%)a
N = 254
S. soneii
N (%)a
N = 88
S. flexneri
N (%)a
N = 152
S. boydii
N (%)a
N = 12
S. dysenteriae
N (%)a
N = 2
No resistance 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Resistance to one antimicrobial class 15 (5.9) 3 (3.4) 12 (7.9) 0 (0.0) 0 (0.0)
Resistance to two antimicrobial classes 37 (14.6) 2 (2.3) 31 (20.4) 3 (25.0) 1 (50.0)
Resistance to three antimicrobial classes 66 (26.0) 39 (44.3) 24 (15.8) 3 (25.0) 0 (0.0)
Resistance to four antimicrobial classes 121 (47.6) 42 (47.7) 73 (48.0) 6 (50.0) 0 (0.0)
Resistance to five antimicrobial classes 15 (5.9) 2 (2.3) 12 (7.9) 0 (0.0) 1 (50.0)
Multidrug-resistanceb 120 (51.3) 44 (56.4) 68 (47.9) 7 (58.3) 1 (50.0)
  1. aProportions based on non-missing data
  2. bResistance to ampicillin and trimethoprim-sulfamethoxazole (AT/S)