From: Inappropriate use of antibiotics for childhood diarrhea case management — Kenya, 2009–2016
Factors | Antibiotic prescribed (%) | Antibiotic not prescribed (%) | Crude odds ratio (95% CI) | Adjustedb odds ratio (95% CI) |
---|---|---|---|---|
Demographics | ||||
Age < 1 | 4/47 (8.51%) | 33/132 (25.0%) | 3.58 (1.20–10.72) | 4.76 (1.46–15.50) |
Male | 21/47 (44.7%) | 73/132 (55.3%) | 1.53 (0.78–2.99) | |
Recent medical history | ||||
Clinic visit within 14 days | 7/47 (14.9%) | 21/132 (15.9%) | 1.08 (0.43–2.74) | |
Clinic visit within 14 days with diarrheal symptom | 3/45 (6.7%) | 8/127 (6.3%) | 0.94 (0.24–3.71) | |
Clinic visit within 14 days with antibiotic treatment | 1/47 (2.1%) | 3/132 (2.3%) | 1.07 (0.11–10.51) | |
Signs and symptoms | ||||
Weight-for-age < −2 | 8/47 (17.0%) | 21/132 (15.9%) | 0.92 (0.38–2.25) | |
Height-for-age < −2 | 23/42 (54.8%) | 46/106 (43.4%) | 0.63 (0.31–1.30) | |
Weight-for-height < − 2 | 3/42 (7.1%) | 7/106 (6.6%) | 0.92 (0.23–3.74) | |
Measured or reported fever | 8/47 (17.0%) | 13/132 (9.85%) | 0.53 (0.21–1.38) | 0.34 (0.11–1.05) |
Cough | 25/47 (53.2%) | 55/132 (41.7%) | 0.63 (0.32–1.22) | 0.54 (0.25–1.17) |
Difficulty breathing | 1/43 (2.33%) | 0/107 (0%) | N/A | |
Sore throat | 0/47 (0%) | 0/131 (0%) | N/A | |
Vomiting | 5/47 (10.6%) | 8/132 (6.1%) | 0.54 (0.17–1.75) | |
Runny nose | 27/47 (57.5%) | 63/132 (47.7%) | 0.68 (0.35–1.32) | |
Sneezing | 6/47 (12.7%) | 16/132 (12.1%) | 0.94 (0.35–2.57) | |
Physical examination | ||||
Restless or irritable | 0/47 (0%) | 0/131 (0%) | N/A | |
Sunken eyes | 1/47 (2.1%) | 0/132 (0%) | N/A | |
Drinks eagerly, thirsty | 2/47 (4.3%) | 0/132 (0%) | N/A | |
Skin tenting | 1/47 (2.1%) | 0/131 (0%) | N/A | |
Signs of anemia | 0/47 (0%) | 1/131 (0.8%) | N/A | |
Crackles/rales | 0/47 (0%) | 1/132 (0.8%) | N/A | |
Clinical diagnoses | ||||
Gastroenteritis | 32/47 (68.1%) | 79/131 (60.3%) | 0.71 (0.35–1.44) | |
Malaria diagnosis | 1/47 (2.1%) | 2/131 (1.5%) | 0.71 (0.06–8.05) | |
Dehydration | 1/47 (2.1%) | 1/131 (0.8%) | 0.35 (0.02–5.78) | |
URTIa | 14/47 (29.8%) | 40/131 (30.5%) | 1.04 (0.50–2.14) | |
Dysentery | 13/47 (27.7%) | 7/131 (5.3%) | 0.15 (0.06–0.40) | 0.10 (0.03–0.34) |
Treatment | ||||
Concurrent ORSa | 37/47 (78.7%) | 83/132 (62.9%) | 0.46 (0.21–1.00) | |
Concurrent zinc | 15/47 (31.9%) | 42/132 (31.8%) | 1.00 (0.49–2.03) |