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Table 3 Multiple linear regression models of nicotine metabolites by job type, Pennsylvania Adult Smoking Study

From: Socioeconomic differences in nicotine exposure and dependence in adult daily smokers

  Unemployed/Retired/ Student/Disabled Blue Collar White Collar
Est 95% CI P-value Est 95% CI P-value Est 95% CI P-value
Nicotine metabolite
 Cotinine
  Intercept 146.65 −5.84 299.13 0.059 136.21 29.14 243.28 0.013 141.19 −67.92 350.29 0.183
  SES PC1 −65.48 − 109.58 −21.38 0.004 13.76 −4.60 32.12 0.141 27.91 −7.87 63.69 0.124
  Age 2.73 −0.29 5.75 0.075 3.18 1.31 5.05 0.001 3.64 0.02 7.27 0.049
  BMI −1.85 −6.01 2.30 0.374 −3.16 −6.07 −0.25 0.034 −4.10 −9.82 1.63 0.156
  FTND score 6.96 −8.14 22.06 0.359 23.22 13.74 32.69 <.001 27.88 11.35 44.41 0.001
  Sex (M vs F) 67.87 −9.70 145.43 0.085 57.57 16.61 98.52 0.006 46.24 −31.31 123.78 0.238
  Adj R2 0.279     0.245     0.209    
  n 57     170     77    
 3HCa
  Intercept 7.88 2.97 12.80 0.002 7.33 4.66 1.00 <.001 1.58 −2.77 5.92 0.472
  SES PC1 0.07 −1.20 1.34 0.915 −0.45 −0.92 0.02 0.059 0.80 0.05 1.55 0.037
  Age 0.11 0.02 0.19 0.014 0.07 0.02 0.12 0.006 0.10 0.03 0.18 0.007
  FTND score 0.09 −0.38 0.57 0.697 0.38 0.12 0.65 0.005 0.87 0.50 1.24 <.001
  Adj R2 0.228     0.230     0.364    
  n 56     168     78    
 TSNMa
  Intercept −1.87 −2.26 −1.49 <.001 −1.73 −1.97 − 1.49 <.001 −2.03 − 2.41 − 1.65 <.001
  SES PC1 −0.12 −0.23 0.00 0.042 −0.01 − 0.05 0.03 0.604 0.07 0.01 0.14 0.027
  Age 0.01 0.00 0.02 0.047 0.01 0.00 0.01 0.001 0.01 0.00 0.02 0.005
  BMI 0.00 −0.01 0.01 0.868 −0.01 −0.02 0.00 0.010 0.00 −0.01 0.01 0.410
  FTND score 0.02 −0.02 0.05 0.391 0.06 0.04 0.08 <.001 0.08 0.05 0.11 <.001
  Sex (M vs F) 0.15 −0.06 0.35 0.152 0.11 0.02 0.20 0.018 0.04 −0.10 0.18 0.602
  Adj R2 0.205     0.2890     0.406    
  n 55     168     77    
  1. Abbreviations: 3HC: 3′-hydroxycotinine, TSNM: Total Salivary Nicotine Metabolites, NMR: Nicotine Metabolite Ratio, CPD: cigarettes per day, BMI: Body mass index, FTND: Fagerström Test for Nicotine Dependence, SES PC1: Socioeconomic status primary principal component
  2. a3HC and TSNM were log-transformed