Survival analysis of time to cure on multi-drug resistance tuberculosis patients in Amhara region, Ethiopia

BMC Public Health

Table 5 Multivariable analysis using Weibull shared Gamma frailty model for the recovery time of MDR-TB patients in Amhara region, Ethiopia

Variables	Categories	Coeff.	T. R(ϕ)	Std Error	Z-value	P > \|z\|	95% CI for ϕ
MDR-TB type	Extra pulmonary	0.05	1.055	0.013	4.34	< 0.001	1.03	1.08
MDR-TB type	Pulmonary⁺		1
Clinical Complication	Yes	0.04	1.041	0.008	5.23	< 0.001	1.025	1.056
Clinical Complication	No⁺		1
Adherence	Fair	0.02	1.021	0.019	1.09	0.28	0.984	1.059
	Poor	0.031	1.032	0.013	2.46	< 0.01	1.006	1.058
	Good⁺		1
Co morbidities	Yes	0.078	1.081	0.015	5.69	< 0.001	1.053	1.111
Co morbidities	No⁺		1
HIV status	Positive	−0.007	0.993	0.014	−0.51	0.613	0.966	1.021
HIV status	Negative⁺		1
Sex	Male	0.028	1.029	0.007	4.02	< 0.001	1.015	1.043
Sex	Female⁺		1
Previous drug use history	Yes	−0.009	0.992	0.008	−1.06	0.291	0.976	1.007
Previous drug use history	No⁺		1
Smoking status	Smoker	−0.051	0.95	0.02	−2.43	0.015	0.9125	0.99
Smoking status	Nonsmoker⁺		1
Sex by HIV status	Male HIV positive	0.037	1.038	0.019	2.03	0.042	1.001	1.075
Sex by HIV status	Female HIV negative⁺		1					1.075
Drug use history by smoker	Drug used with smoker	0.071	1.073	0.025	3.09	0.002	1.026	1.122
Drug use history by smoker	Nondrug use with nonsmoker⁺		1
Cons		2.99	19.879	0.136	438.53	< 0.001	19.615	20.146
Ln(λ)			3.722	0.106	35.02	< 0.001	3.514	3.931
Ln(θ)			−3.986	1.775	−2.25	0.03	−7.464	−0.508
λ			41.364	4.397			33.585	50.946
γ			0.024	0.003			0.02	0.03
θ			1.24	0.3608			0.695	2.212

γ Shape parameter, λ Scale parameter,θ Frailty parameter, ⁺ reference category, CI Confidence interval, Std Error Standard Error, ϕ Time ratio: the ratio for groups of median time to recovery

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