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Table 2 Risk for outcomes by RRF after stratification by age group

From: Influence of age on the effect of reduced renal function on outcomes in patients with coronary artery disease

Age group Age ≤ 59 yrs Age 60 to 69 yrs Age ≥ 70 yrs
Outcomes HR (95% CI) HR (95% CI) HR (95% CI)
All-cause mortality
 Unadjusted 6.67 (3.12–14.25) 3.03 (1.81–5.05) 1.78 (1.31–2.42)
 Adjusted
  Model 1a 5.03 (2.32–10.89) 2.79 (1.67–4.67) 1.68 (1.23–2.28)
  Model 2b 4.83 (2.22–10.51) 2.73 (1.63–4.58) 1.76 (1.29–2.39)
  Model 3c 2.57 (1.04–6.37) 2.00 (1.17–3.42) 1.46 (1.06–2.02)
Cardiac mortality
 Unadjusted 5.19 (1.92–14.00) 3.40 (1.84–6.30) 1.69 (1.09–2.62)
 Adjusted
  Model 1a 4.08 (1.49–11.18) 3.13 (1.69–5.80) 1.56 (1.00–2.42)
  Model 2b 3.85 (1.40–10.64) 3.09 (1.66–5.75) 1.65 (1.06–2.57)
  Model 3c 1.18 (0.31–4.44) 2.03 (1.07–3.85) 1.18 (0.74–1.90)
  1. RRF means eGFR<60 ml/min/1.73 m2
  2. a Model 1 adjusted for age; b Model 2 adjusted for factors of Model 1 and gender; c Model 3 adjusted for factors of Model 2 and other factors: pre-hypertension, pre-diabetes mellitus, systolic blood pressure, Killip class, severity of CAD, diagnosis of ACS, and treatment of PCI
  3. Abbreviations: RRF reduced renal function; eGFR estimated glomerular filtration rate, HR hazard ratio, CI confidence interval, CAD coronary artery disease, ACS acute coronary syndrome, PCI percutaneous coronary intervention
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