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Table 2 Time to first cigarette and other risk factors for atherosclerosis in long-term heavy smokers

From: Nicotine dependence as an independent risk factor for atherosclerosis in the National Lung Screening Trial

Effect Odds ratios and their 95% CIs
All matched samples
N = 166 cases, 286 controls
Aortic Atherosclerosisa
N = 95 cases, 164 controls
Coronary atherosclerosis only
N = 71 cases, 122 controls
TTFC
  ≤ 5 min Reference Reference Reference
 6–29 min 0.72 (0.44–1.16) 0.54 (0.27–1.10) 0.9 (0.45–1.82)
 30–60 min 0.94 (0.49–1.82) 1.08 (0.46–2.52) 0.9 (0.29–2.74)
  > 60 min 0.49 (0.24–1.00) 0.24 (0.08–0.69) 1.27 (0.43–3.74)
BMI 0.95 (0.91–1.00) 0.93 (0.86–0.99) 0.98 (0.91–1.05)
Diabetes 1.45 (0.79–2.64) 0.58 (0.20–1.68) 2.58 (1.16–5.76)
Hypertension 1.78 (1.15–2.74) 2.34 (1.25–4.38) 1.36 (0.72–2.59)
Heart Attack 1.22 (0.70–2.13) 1.58 (0.71–3.52) 0.98 (0.42–2.29)
  1. All estimates were adjusted for the other covariates in the model. a Includes 40 cases with co-diagnosis of coronary atherosclerosis