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Table 2 Differences in pooled mean costs and effects (95% CI), incremental cost-effectiveness ratios, and the distribution of incremental cost-effect pairs around the quadrants of the cost-effectiveness planes

From: Economic evaluation of telephone-based weight loss support for patients with knee osteoarthritis: a randomised controlled trial

Analysis

 

Outcomes

∆C (95% CI)

∆E (95% CI)

ICER

Distribution CE-plane (%)

AUD

Points

AUD/point

NEc

SEd

SWe

NWf

Primary analysisa

Societal perspective

QALYs

1197 (−2962 to 6139)

0.00 (−0.02 to 0.02)

581,828

26.2

15.5

20.8

37.5

Pain intensity

1197 (− 2945 to 6126)

0.64 (−0.49 to 1.77)

1858

6.2

5.8

30.3

57.6

Disability

1197 (− 2884 to 6151)

0.80 (−6.86 to 8.47)

1495

21.7

19.4

17.0

41.9

  

Weight

1197 (− 2941 to 6153)

-0.02 (−3.46 to 3.42)

−58,194

30.6

18.8

17.6

32.9

  

BMI

1197 (− 2864 to 6122)

0.11 (−1.16 to 1.39)

10,455

26.8

16.1

20.3

36.8

Sensitivity analysisb

Per protocol

QALYs

− 958 (− 5801 to 2790)

0.00 (−0.03 to 0.04)

−203,221

24.3

36.8

24.5

14.4

Pain intensity

−958 (− 5803 to 2869)

0.70 (−0.75 to 2.15)

− 1370

6.3

10.9

50.6

32.2

Disability

−958 (− 5819 to 2792)

1.21 (− 9.43 to 11.85)

−790

17.8

26.2

35.3

20.6

  

Weight

−958 (− 5782 to 2804)

1.04 (−4.48 to 6.55)

− 922

13.1

22.8

38.6

25.5

  

BMI

−958 (− 5785 to 2884)

0.62 (−1.42 to 2.65)

− 1553

10.3

18.4

43.1

28.1

Secondary analysisa

Healthcare perspective

QALYs

798 (− 3175 to 5686)

−0.00 (−0.02 to 0.02)

−387,820

24.1

17.5

24.0

34.3

Pain intensity

798 (− 3197 to 5835)

0.64 (−0.49 to 1.78)

1238

5.9

6.3

35.3

52.5

Disability

798 (− 3203 to 5663)

0.80 (−6.9 to 8.47)

994

19.7

21.4

19.7

39.2

  

Weight

798 (− 3234 to 5670)

−0.21 (− 3.46 to 3.42)

−38,598

28.4

21.4

19.8

30.3

  

BMI

798 (− 3281 to 5618)

0.11 (−1.16 to 1.39)

6968

24.9

18.3

23.1

33.7

  1. C Costs, E Effects
  2. Note: costs are expressed in 2016 Australian Dollars (AUD)
  3. aIntervention n = 59, Control n = 60
  4. bIntervention n = 20, Control n = 60
  5. cThe northeast (NE) quadrant of the CE plane, indicating that the intervention is more effective and more costly than control
  6. dThe southeast (SE) quadrant of the CE plane, indicating that the intervention is more effective and less costly than control
  7. eThe southwest (SW) quadrant of the CE plane, indicating that the intervention is less effective and less costly than control
  8. fThe northwest (NW) quadrant of the CE plane, indicating that the intervention is less effective and more costly than control