Table 2 Components of metabolic syndrome by cohort, categorised by normal glucose tolerance, prediabetes, newly diagnosed diabetes and known diabetes
| Â | Normal glucose tolerance | Prediabetes | Newly diagnosed diabetes | Known diabetes |
|---|---|---|---|---|
Total % (n) | ||||
 KORA-F4 | 60.5 (1774) | 28.4 (834) | 3.0 (87) | 8.1 (237) |
 SHIP-TREND | 45.3 (1151) | 34.9 (885) | 5.6 (142) | 14.2 (361) |
Age (years) mean (std) | ||||
 KORA-F4 | 51.5 (12.2) | 60.6 (11.3) | 64.8 (9.7) | 66.9 (8.6) |
 SHIP-TREND | 48.6 (12.3) | 55.2 (11.7) | 61.6 (9.3) | 65.0 (9.3) |
Body mass index (kg/m2) mean (SD) | ||||
 KORA-F4 | 26.3 (4.3) | 29.1 (4.7) | 31.1 (4.4) | 31.5 (5.4) |
 SHIP-TREND | 26.3 (4.3) | 29.3 (4.7) | 31.3 (5.2) | 33.0 (5.8) |
Systolic blood pressure (mmHg) mean (SD) | ||||
 KORA-F4 | 117.4 (16.9) | 128.1 (18.5) | 132.6 (16.8) | 132.7 (19.6) |
 SHIP-TREND | 121.0 (15.7) | 130.7 (16.8) | 135.7 (19.3) | 138.5 (19.9) |
Diastolic blood pressure (mmHg) mean (SD) | ||||
 KORA-F4 | 74.2 (9.6) | 77.3 (10.2) | 77.9 (10.5) | 74.6 (10.5) |
 SHIP-TREND | 75.3 (9.4) | 79.3 (9.7) | 79.1 (10.8) | 78.4 (10.8) |
Fasting glucose (mmol/l) | ||||
 KORA-F4 | 5.0 (0.3) | 5.7 (0.5) | 6.7 (1.3) | NA |
 SHIP-TREND | 5.1 (0.3) | 5.9 (0.4) | 7.3 (1.8) | NA |
2-h glucose (mmol/l) | ||||
 KORA-F4 | 5.3 (1.1) | 7.3 (1.8) | 12.0 (2.8) | NA |
 SHIP-TREND | 5.5 (1.1) | 7.1 (1.7) | 12.6 (3.5) | NA |
HbA1c (%) mean (SD) | ||||
 KORA-F4 | 5.3 (0.3) | 5.6 (0.3) | 6.1 (0.7) | 6.8 (1.1) |
 SHIP-TREND | 5.1 (0.5) | 5.3 (0.5) | 5.9 (1.0) | 6.7 (1.3) |
HbA1c (mmol/mol) mean (SD) | ||||
 KORA-F4 | 34.7 (3.2) | 37.6 (3.7) | 43.2 (7.6) | 51.1 (12.5) |
 SHIP-TREND | 32.3 (5.9) | 34.7 (5.6) | 41.1 (10.8) | 49.8 (13.7) |
HOMA-IR median (IQR) | ||||
 KORA-F4 | 1.7 (1.2–2.3) | 2.8 (2.0–4.2) | 5.3 (3.2–7.3) | 5.2 (3.5–8.1) |
 SHIP-TREND | 1.9 (1.3–2.6) | 3.2 (2.3–4.6) | 5.9 (3.7–8.4) | NA |
HDL-cholesterol (mmol/l) mean (SD) | ||||
 KORA-F4 | 1.5 (0.4) | 1.4 (0.4) | 1.3 (0.3) | 1.2 (0.3) |
 SHIP-TREND | 1.5 (0.4) | 1.4 (0.3) | 1.3 (0.4) | 1.2 (0.3) |
Triglycerides (mmol/l) median (IQR) | ||||
 KORA-F4 | 1.0 (0.7–1.5) | 1.4 (1.0–2.0) | 1.8 (1.2–2.6) | 1.6 (1.1–2.3) |
 SHIP-TREND | 1.1 (0.8–1.5) | 1.4 (1.1–2.0) | 1.9 (1.3–2.8) | 2.1 (1.5–3.0) |
hsCRP (mg/l)a median (IQR) | ||||
 KORA-F4 | 0.9 (0.5–1.9) | 1.4 (0.7–2.7) | 2.8 (1.2–4.7) | 1.8 (0.9–3.2) |
 SHIP-TREND | 1.0 (0.6–2.1) | 1.3 (0.7–2.5) | 1.9 (0.9–3.7) | 2.1 (1.0–4.2) |
Macrovascular disease % (n) | ||||
KORA-F4 | 5.3 (94) | 11.1 (92) | 12.6 (11) | 24.9 (59) |
SHIP-TREND | 6.1 (70) | 10.0 (88) | 19.7 (28) | 32.8 (118) |