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Table 1 Comparison of PMTCT Options A, B and B+ [7, 8]

From: Impact of maternal ART on mother-to-child transmission (MTCT) of HIV at six weeks postpartum in Rwanda

Timing

Option A

Option B

Option B+

Mother

Baby

Mother

Baby

Mother

Baby

Antepartum

ZDV from 14 weeks onward

 

Three drug ARV combination from 14 weeks until end of breastfeeding

 

Three drug ARV combination (from 1st HIV+ test) for life

 

Intrapartum

Single-dose NVP

     

Postpartum

1 week ZDV + 3TC

NVP for 6 weeks or until end of breastfeeding

 

NVP or ZDV until 6 weeks

 

NVP or ZDV until 6 weeks

  1. ZDV zidovudine, NVP nevirapine, 3TC, lamiduvine, ARV antiretroviral