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Table 2 – Comparison of treatment paradigms for BP loweringa

From: Cardiovascular disease risk and comparison of different strategies for blood pressure management in rural India

Treatment paradigm for BP lowering Population treated
% (95% CI)
CVD events averted over 10 years due to treatment
n (95% CI)
Estimated percentage reduction of CVD events averted over 10 years compared to no treatment†
% (95% CI)
Percentage change in number treated compared to current practice
% (95% CI)
Percentage change in number of events averted over 10 years compared to current practice
% (95% CI)
Percentage change in number treated compared to “hypertension” paradigm
% (95% CI)
Percentage change in number of events averted over 10 years compared to “hypertension” paradigm
% (95% CI)
Current practice 19·6
(18·4–20·9)
502
(471–533)
5·3
(5·1–5·5)
Treatment of “hypertension” (BP > 140/90 mmHg) 32·6
(30·8–34·5)
869
(820–919)
9·2
(9·0–9·5)
+ 66·2
(65·8–66·5)
+ 74·2
(72·5–76·0)
Treatment according to NPCDCS guidelines 21·0
(19·9–22·2)
886
(838–934)
9·4
(9·1–9·7)
+ 7·2
(6·9–7·4)
+ 77·3
(75·6–79·0)
−35.5
(−35.2--35.8)
+ 1.7
(1.4–2.2)
Treatment of all at intermediate and high risk 23·2
(22·0–24·3)
936
(889–983)
9·9
(9·7–10·2)
+ 17·9
(17·6–18·2)
+ 87·2
(85·8–88·5)
−29.1
(−28.8--29.3)
+ 7.4
(6.7–8·3)
Treatment of all at high risk 17·9
(16·9–18·8)
812
(768–856)
8·6
(8·4–8·9)
−9·0
(−8·8--9·2)
+ 62·7
(60·7–64·6)
−45.2
(−44.9--45.5)
−6.6
(−5.9--7.4)
Treatment of all above 45 years of age 76·5
(75·4–77·6)
1233
(1216–1250)
13·0
(12·7–13·3)
+ 289·5
(289.2–289.8)
+ 145·7
(144.6–146.8)
+ 134.4
(133.7–135.6)
+ 41.0
(37.1–45.9)
Treatment of all above 55 years of age 44·5
(43·2, 45·8)
909
(883–935)
9·6
(9·3–9·9)
+ 126·6
(126.3–126.9)
+ 80·7
(78.9–82.4)
+ 36.4
(36.1–36.7)
+ 3.7
(3.2–4.3)
  1. aWeighted estimates †Estimated number of CVD events over 10 years in the untreated population is 9442. This estimate is based on the population risk distribution after adjustment of BP levels in those on BP lowering treatment
  2. BP blood pressure, CVD cardiovascular disease, NPCDCS National Program on prevention and control of Cancer, Diabetes, Cardiovascular diseases and Stroke