Table 2 – Comparison of treatment paradigms for BP loweringa
| Treatment paradigm for BP lowering |
Population treated % (95% CI) |
CVD events averted over 10 years due to treatment n (95% CI) |
Estimated percentage reduction of CVD events averted over 10 years compared to no treatment† % (95% CI) |
Percentage change in number treated compared to current practice % (95% CI) |
Percentage change in number of events averted over 10 years compared to current practice % (95% CI) |
Percentage change in number treated compared to “hypertension” paradigm % (95% CI) |
Percentage change in number of events averted over 10 years compared to “hypertension” paradigm % (95% CI) |
|---|---|---|---|---|---|---|---|
| Current practice |
19·6 (18·4–20·9) |
502 (471–533) |
5·3 (5·1–5·5) | – | – | – | – |
| Treatment of “hypertension” (BP > 140/90 mmHg) |
32·6 (30·8–34·5) |
869 (820–919) |
9·2 (9·0–9·5) |
+ 66·2 (65·8–66·5) |
+ 74·2 (72·5–76·0) | – | – |
| Treatment according to NPCDCS guidelines |
21·0 (19·9–22·2) |
886 (838–934) |
9·4 (9·1–9·7) |
+ 7·2 (6·9–7·4) |
+ 77·3 (75·6–79·0) |
−35.5 (−35.2--35.8) |
+ 1.7 (1.4–2.2) |
| Treatment of all at intermediate and high risk |
23·2 (22·0–24·3) |
936 (889–983) |
9·9 (9·7–10·2) |
+ 17·9 (17·6–18·2) |
+ 87·2 (85·8–88·5) |
−29.1 (−28.8--29.3) |
+ 7.4 (6.7–8·3) |
| Treatment of all at high risk |
17·9 (16·9–18·8) |
812 (768–856) |
8·6 (8·4–8·9) |
−9·0 (−8·8--9·2) |
+ 62·7 (60·7–64·6) |
−45.2 (−44.9--45.5) |
−6.6 (−5.9--7.4) |
| Treatment of all above 45 years of age |
76·5 (75·4–77·6) |
1233 (1216–1250) |
13·0 (12·7–13·3) |
+ 289·5 (289.2–289.8) |
+ 145·7 (144.6–146.8) |
+ 134.4 (133.7–135.6) |
+ 41.0 (37.1–45.9) |
| Treatment of all above 55 years of age |
44·5 (43·2, 45·8) |
909 (883–935) |
9·6 (9·3–9·9) |
+ 126·6 (126.3–126.9) |
+ 80·7 (78.9–82.4) |
+ 36.4 (36.1–36.7) |
+ 3.7 (3.2–4.3) |